Results 41 to 50 of about 279,855 (305)

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

GDSCalc: A Web-Based Application for Evaluating Discrete Graph Dynamical Systems.

PLoS ONE, 2015
Discrete dynamical systems are used to model various realistic systems in network science, from social unrest in human populations to regulation in biological networks.
Sherif H Elmeligy Abdelhamid, Chris J Kuhlman, Madhav V Marathe, Henning S Mortveit, S S Ravi   +4 more
doaj   +1 more source

Finite Chaoticity and Pairwise Sensitivity of a Strong-Mixing Measure-Preserving Semi-Flow

Axioms, 2023
Chaos is a common phenomenon in nature and social sciences. As is well known, chaos has multiple definitions, and there are both differences and connections between them.
Risong Li, Jingmin Pi, Yongjiang Li, Tianxiu Lu, Jianjun Wang, Xianfeng Ding   +5 more
doaj   +1 more source

Discrete Dynamical Systems Embedded in Cantor Sets

, 2006
While the notion of chaos is well established for dynamical systems on manifolds, it is not so for dynamical systems over discrete spaces with $ N $ variables, as binary neural networks and cellular automata.
Alberto Verjovsky, Atkinson K. E., Choquet-Bruhat Y., Devaney R., Fabio Benatti, Federico Zertuche, Hertz J., Kauffman S. A., Pontrjagin L., Weisbuch G., Wiggins S., Wolfram S.   +11 more
core   +3 more sources

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Parallel Dynamical Systems over Graphs and Related Topics: A Survey

Journal of Applied Mathematics, 2015
In discrete processes, as computational or genetic ones, there are many entities and each entity has a state at a given time. The update of states of the entities constitutes an evolution in time of the system, that is, a discrete dynamical system.
Juan A. Aledo, Silvia Martinez, Jose C. Valverde   +2 more
doaj   +1 more source

Development of a Personalized Visualization and Analysis Tool to Improve Clinical Care in Complex Multisystem Diseases With Application to Scleroderma

Arthritis Care &Research, EarlyView.
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim, John Scott, Lauren Fisher, Lauren N. Smith, Willie Stewart, Adrianne Woods, Rob Smithwright, Diane Koher, Parastoo Aslanbeik, Aalok B. Shah, Brad Tibbils, Samantha I. Pitts, Ayse P. Gurses, Yushi Yang, Ana‐Maria Orbai, Antony Rosen, Laura K. Hummers, Scott L. Zeger, Ami A. Shah   +18 more
wiley   +1 more source

GROUPOIDS AND IRREVERSIBLE DISCRETE DYNAMICAL SYSTEMS II [PDF]

Fiabilitate şi Durabilitate, 2012
The purpose of this paper is to study the topology of the orbit space of an irreversible discrete dynamical system (X, ) seen as a principal groupoid associated to the groupoid G(X,,E) introduced in [1] (where E is an equivalence relation on X).
Mădălina Roxana Buneci
doaj  

Stability and convergence in discrete convex monotone dynamical systems

, 2010
We study the stable behaviour of discrete dynamical systems where the map is convex and monotone with respect to the standard positive cone. The notion of tangential stability for fixed points and periodic points is introduced, which is weaker than ...
B. Lemmens, B. Lemmens, Bas Lemmens, G. Cooman de, H. Schneider, H.L. Smith, M. Akian, M. Akian, M.G. Crandall, M.G. Kreĭn, M.W. Hirsch, M.W. Hirsch, Marianne Akian, N. Dancer, P. Alexandroff, P. Hess, P. Poláčik, P. Takáč, R.D. Nussbaum, R.D. Nussbaum, R.D. Nussbaum, S. Boyd, Stéphane Gaubert, U. Krause, U.G. Rothblum, U.G. Rothblum   +25 more
core   +1 more source