Results 41 to 50 of about 127,686 (263)
Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas +3 more
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Spectral element discretization of the Maxwell equations [PDF]
Mathematics of Computation, 1999 We consider a variational problem which is equivalent to the electromagnetism system with absorbing conditions on a part of the boundary, and we prove that it is well-posed. Next we propose a discretization relying on a finite difference scheme for the time variable and on spectral elements for the space variables, and we derive error estimates between
Faker Ben Belgacem, Christine Bernardi
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Applied Sciences, 2023 Aiming at the lack of a precise discrete element model in the simulation analysis of corn straw crushing, this paper established bond models with different structure and particle models with different properties of corn straw based on Hertz-Mindlin with ...
Wenhang Liu +5 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
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Interfacing Finite Element and Boundary Element Discretizations
Applied Mathematical Modelling, 1981 This paper reviews critically various implementation methods for coupling a mechanical finite element model to an infinite external acoustic domain discretized through boundary-element techniques. The associated physical problem is that of a three-dimensional structure submerged in an acoustic fluid, and impinged by a pressure shock wave.
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Agriculture, 2023 Due to the lack of accurate discrete element simulation model parameters in the design optimization process of key agricultural machinery components in the whole mechanization technology system of cotton generation, the optimization and improvement of ...
Deli Jiang +5 more
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Numerical prediction of dynamic stability loss of a flexible cylindrical shell in a granular medium [PDF]
Biuletyn Wojskowej Akademii Technicznej, 2019 The paper presents an application of the discrete element method for an analysis of dynamical stability loss of the flexible cylindrical shell section interacting with a model granular medium.
Paweł Szklennik, Grzegorz Bąk
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source