Results 41 to 50 of about 94,516 (265)
International Journal for Computational Civil and Structural Engineering, 2023 Localization of solution of the problem of three-dimensional theory of elasticity with the use of B-spline discrete-continual finite element method (specific version of wavelet-based discrete-continual finite ele-ment method) is under consideration in ...
Marina Mozgaleva, Pavel Akimov
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
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A Fully Discrete Evolving Surface Finite Element Method [PDF]
SIAM Journal on Numerical Analysis, 2012 In this paper we consider a time discrete evolving surface finite element method for the advection and diffusion of a conserved scalar quantity on a moving surface. In earlier papers using a suitable variational formulation in time dependent Sobolev space we proposed and analyzed a finite element method using surface finite elements on evolving ...
Gerhard Dziuk, Charles M. Elliott
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
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GeosciencesThe dynamic fracture of rocks under impact loads has many engineering applications such as rock blasting. This study reviews the recent achievements of investigating rock dynamic fracturing and its application in rock blasting using computational ...
Muhammad Kamran +5 more
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Numerical prediction of dynamic stability loss of a flexible cylindrical shell in a granular medium [PDF]
Biuletyn Wojskowej Akademii Technicznej, 2019 The paper presents an application of the discrete element method for an analysis of dynamical stability loss of the flexible cylindrical shell section interacting with a model granular medium.
Paweł Szklennik, Grzegorz Bąk
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
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Modeling of Asphalt Concrete While Using Discrete Element Method
Наука и техника, 2019 The paper considers a mathematical model which is used to study a composite material similar in structure to asphalt concrete and it takes into account presence of solid particles of different sizes and a soft and plastic binder.
V. V. Alekseenko +2 more
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Dual Virtual Element Method for Discrete Fractures Networks [PDF]
SIAM Journal on Scientific Computing, 2018 Discrete fracture networks is a key ingredient in the simulation of physical processes which involve fluid flow in the underground, when the surrounding rock matrix is considered impervious. In this paper we present two different models to compute the pressure field and Darcy velocity in the system.
Fumagalli A., Keilegavlen E.
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
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