Results 51 to 60 of about 94,516 (265)

Improvement of spheropolyhedral-based discrete element method and its application in fracture process of rock mass

open access: yesYantu gongcheng xuebao
In order to accurately simulate the evolution process of fractures, a three-dimensional deformable spheropolyhedral-based discrete element method is proposed by combining the finite element method with the spheropolyhedral-based discrete element method ...
ZHANG Decang , MAO Jia , DAI Miaolin , SHAO Linyu , ZHAO Lanhao
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Analysis of Optimal RAP Content Based on Discrete Element Method

open access: yesAdvances in Materials Science and Engineering, 2022
Methods of recycling a large amount of waste asphalt mixture generated in pavement maintenance and decreasing the waste of existing resources are one of the problems that will be solved in the future.
Lei Wang, Xiucheng Yang
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

ABOUT SOLUTION OF MULTIPOINT BOUNDARY PROBLEMS OF THREE-DIMENSIONAL STRUCTURAL ANALYSIS WITH THE USE OF COMBINED APPLICATION OF FINITE ELEMENT METHOD AND DISCRETE-CONTINUAL FINITE ELEMENT METHOD. PART 1: FORMULATION AND BASIC PRINCIPLES OF APPROXIMATION

open access: yesInternational Journal for Computational Civil and Structural Engineering, 2018
The distinctive paper is devoted to formulation and basic principles of approximation of multipoint boundary problem of static analysis of three-dimensional structure with the use of combined application of finite element method and discrete-continual ...
Pavel A. Akimov, Oleg A. Negrozov
doaj   +1 more source

Discrete Element Method for Sand-Structure Interaction

open access: yesDiscrete Element Methods, 2002
3rd International Conference on Discrete Element Methods: 23 September 2002, Santa Fe, New ...
Zeghal, M., Edil, T. B., Plesha, M. E.
openaire   +3 more sources

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu   +10 more
wiley   +1 more source

The Virtual Element Method on Anisotropic Polygonal Discretizations

open access: yes, 2019
In recent years, the numerical treatment of boundary value problems with the help of polygonal and polyhedral discretization techniques has received a lot of attention within several disciplines. Due to the general element shapes an enormous flexibility is gained and can be exploited, for instance, in adaptive mesh refinement strategies.
Antonietti, Paola F.   +3 more
openaire   +1 more source

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