Results 61 to 70 of about 117,272 (312)

Numerical prediction of dynamic stability loss of a flexible cylindrical shell in a granular medium [PDF]

Biuletyn Wojskowej Akademii Technicznej, 2019
The paper presents an application of the discrete element method for an analysis of dynamical stability loss of the flexible cylindrical shell section interacting with a model granular medium.
Paweł Szklennik, Grzegorz Bąk
doaj   +1 more source

Dual Virtual Element Method for Discrete Fractures Networks [PDF]

SIAM Journal on Scientific Computing, 2018
Discrete fracture networks is a key ingredient in the simulation of physical processes which involve fluid flow in the underground, when the surrounding rock matrix is considered impervious. In this paper we present two different models to compute the pressure field and Darcy velocity in the system.
Fumagalli A., Keilegavlen E.
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Discrete Mechanical Interpolation of Keyframes [PDF]

, 2008
Advances in computer hardware and software have made it possible to use physical simulation methods to add unprecedented degrees of realism to computer animations.
Yang, Weiwei
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Improvement of spheropolyhedral-based discrete element method and its application in fracture process of rock mass

Yantu gongcheng xuebao
In order to accurately simulate the evolution process of fractures, a three-dimensional deformable spheropolyhedral-based discrete element method is proposed by combining the finite element method with the spheropolyhedral-based discrete element method ...
ZHANG Decang , MAO Jia , DAI Miaolin , SHAO Linyu , ZHAO Lanhao
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Modeling of Asphalt Concrete While Using Discrete Element Method

Наука и техника, 2019
The paper considers a mathematical model which is used to study a composite material similar in structure to asphalt concrete and it takes into account presence of solid particles of different sizes and a soft and plastic binder.
V. V. Alekseenko, K. Yu. Vabishchevich, E. V. Verkhoturova   +2 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

ABOUT SOLUTION OF MULTIPOINT BOUNDARY PROBLEMS OF THREE-DIMENSIONAL STRUCTURAL ANALYSIS WITH THE USE OF COMBINED APPLICATION OF FINITE ELEMENT METHOD AND DISCRETE-CONTINUAL FINITE ELEMENT METHOD. PART 1: FORMULATION AND BASIC PRINCIPLES OF APPROXIMATION

International Journal for Computational Civil and Structural Engineering, 2018
The distinctive paper is devoted to formulation and basic principles of approximation of multipoint boundary problem of static analysis of three-dimensional structure with the use of combined application of finite element method and discrete-continual ...
Pavel A. Akimov, Oleg A. Negrozov
doaj   +1 more source