Results 61 to 70 of about 12,504 (308)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Implementation of a Discrete Element Method for the space-time modeling of loading in the case of a soft shock: qualitative approach [PDF]

, 2011
The aim of this study is to modelize the space-time loading induced on a target by a deformable impactor, in the case of a ”soft” shock.The originality of this work resides in the use of discrete elements to model the behaviour of the impactor, where ...
DUPLESSIS KERGOMARD, Yann, DAU, Frédéric, IORDANOFF, Ivan   +2 more
core  

A mesoscopic model using the discrete element method for impacts on dry fabrics [PDF]

, 2016
Dry fabrics can be investigated in aeronautic field to contain debris. Such structures are most of the time modeled with finite elements leading to heavy time calculations especially due to contact treatment.
DAU, Frédéric, J. Girardot, GIRARDOT, Jeremie, F. Dau   +3 more
core   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Simulation of shockless spalling fragmentation using the Discrete Element Method (DEM)

In the present study a Discrete Element Method (DEM) is considered to model the dynamic behaviour and fragmentation mechanisms of alumina ceramic under high strain-rate shockless loading. GEPI (high-pulsed power) spalling experiments are simulated.
FORQUIN, Pascal, GIRARDOT, Jérémie, BRÉMAUD, Luc, MALAISE, Frédéric   +3 more
core   +1 more source

Planetary rover locomotion on soft granular soils - Efficient adaption of the rolling behaviour of nonspherical grains for discrete element simulations [PDF]

, 2013
In consequence of growing interests of science exploration on our solar system’s planets and moons, increased mobility demands are arising for planetary exploration vehicles.
Lichtenheldt, R., Schäfer, B., Lichtenheldt, Roy, Schaefer, Bernd   +3 more
core  

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Discrete element modeling of deformable particles in YADE

SoftwareX, 2017
In this paper we describe the open-source discrete element framework YADE and the implementation of a new deformation engine. YADE is a highly expandable software package that allows the simulation of current industrial problems in the field of granular ...
Martin Haustein, Anton Gladkyy, Rüdiger Schwarze   +2 more
doaj   +1 more source