Results 71 to 80 of about 1,409,098 (301)

Operational and Variational Formulations of Boundary Problems of Anisotropic Plate Analysis, Adapted for Application Within Discrete-Continual Methods

MATEC Web of Conferences, 2017
This paper is devoted to operational and variational formulations [1] of boundary problems of anisotropic plate analysis (with the use of so-called method of extended domain [2]), adapted for applications within discrete-continual methods (discrete ...
Akimov Pavel, Sidorov Vladimir, Wójcicki Zbigniew   +2 more
doaj   +1 more source

Simulation of discrete cracks driven by nearly incompressible fluid via 2D combined finite‐discrete element method

International journal for numerical and analytical methods in geomechanics (Print), 2019
In this work, we propose a novel hydraulic solver in order to simulate key mechanisms that control fluid‐driven cracks in the framework of the combined finite‐discrete element method (FDEM).
Z. Lei, E. Rougier, A. Munjiza, H. Viswanathan, E. Knight   +4 more
semanticscholar   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Study on numerical simulation method for vibration characteristics of shell embedded with acoustic black hole

Zhongguo Jianchuan Yanjiu, 2019
[Objectives] To study a numerical simulation method for a plate embedded with a two-dimensional acoustic black hole,[Methods] a method for discrete modeling of the structure with acoustic black hole by a shell element is proposed. Firstly,an example of a
Wang Bohan, Yang Deqing, Xia Lifu
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

The Müntz spectral element method for the numerical solutions of regularized long wave equation

Franklin Open
This paper introduces new bases derived from Müntz polynomials for application in the spectral element method. Within this framework, we demonstrate that the mass and stiffness matrices exhibit matrix with three non-zero diagonals and diagonal structures,
Mahmoud Lotfi, Amjad Alipanah
doaj   +1 more source

Refinement and application of variable particle-size methods in 3D discrete element modelling for large-scale problems

Yantu gongcheng xuebao, 2017
A refinement method is proposed to solve the difference in the macroscopic elasticity and the interpenetration in interface area between different particle-size areas in the DEM.
DENG Yi-bing 1, YANG Yan-cheng 2, 1, SHI Dan-da 1 , LIU Wen-bai 1
doaj   +1 more source

Discrete Element Method for Sand-Structure Interaction

Discrete Element Methods, 2002
3rd International Conference on Discrete Element Methods: 23 September 2002, Santa Fe, New ...
Zeghal, M., Edil, T. B., Plesha, M. E.
openaire   +3 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

A nonconforming scheme for non-Fickian flow in porous media

Journal of Inequalities and Applications, 2017
In this paper, we construct a semi-discrete scheme and a fully discrete scheme using the Wilson nonconforming element for the parabolic integro-differential equation arising in modeling the non-Fickian flow in porous media by the interior penalty method.
Peizhen Wang, Liying Jiang, Shaochun Chen   +2 more
doaj   +1 more source