Results 71 to 80 of about 932,059 (284)

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Application of Discrete Element Methods to the Problem of Rock Bumps

Acta Polytechnica, 2002
This paper is a continuation of a previous paper by the authors. Applications of two discrete element methods (DEM) to several fields of geotechnics are discussed.
P. P. Procházka, M. G. Kugblenu
doaj  

Operational and Variational Formulations of Boundary Problems of Anisotropic Plate Analysis, Adapted for Application Within Discrete-Continual Methods

MATEC Web of Conferences, 2017
This paper is devoted to operational and variational formulations [1] of boundary problems of anisotropic plate analysis (with the use of so-called method of extended domain [2]), adapted for applications within discrete-continual methods (discrete ...
Akimov Pavel, Sidorov Vladimir, Wójcicki Zbigniew   +2 more
doaj   +1 more source

Discrete Element Method for Sand-Structure Interaction

Discrete Element Methods, 2002
3rd International Conference on Discrete Element Methods: 23 September 2002, Santa Fe, New ...
Zeghal, M., Edil, T. B., Plesha, M. E.
openaire   +3 more sources

Discrete Element Method in der Geotechnik [PDF]

PAMM, 2007
AbstractIn der Discrete Element Method (DEM) werden Böden als Granulat betrachtet, das aus einem System einzelner Partikel besteht, dieüber Kontaktkräfte miteinander in Wechselwirkung stehen und sich gegeneinander verschieben können. In dem hier verwendeten zweidimensionalen Modell werden die Partikel als konvexe unregelmäßige Polygone modelliert ...
E. Heesen, E. Kreuzer
openaire   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Study on numerical simulation method for vibration characteristics of shell embedded with acoustic black hole

Zhongguo Jianchuan Yanjiu, 2019
[Objectives] To study a numerical simulation method for a plate embedded with a two-dimensional acoustic black hole,[Methods] a method for discrete modeling of the structure with acoustic black hole by a shell element is proposed. Firstly,an example of a
Wang Bohan, Yang Deqing, Xia Lifu
doaj   +1 more source

Numerical Experiments for Darcy Flow on a Surface Using Mixed Exterior Calculus Methods [PDF]

, 2011
There are very few results on mixed finite element methods on surfaces. A theory for the study of such methods was given recently by Holst and Stern, using a variational crimes framework in the context of finite element exterior calculus. However, we are
Hirani, Anil N., Kalyanaraman, Kaushik
core  

The Virtual Element Method on Anisotropic Polygonal Discretizations

, 2019
In recent years, the numerical treatment of boundary value problems with the help of polygonal and polyhedral discretization techniques has received a lot of attention within several disciplines. Due to the general element shapes an enormous flexibility is gained and can be exploited, for instance, in adaptive mesh refinement strategies.
Antonietti, Paola F., Berrone, Stefano, Verani, Marco, WEISSER, STEFFEN   +3 more
openaire   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source