Results 31 to 40 of about 114,161 (294)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Event-Triggered Continuous-Discrete Kalman Filter With Controllable Estimation Error

open access: yesIEEE Access, 2018
In this paper, we first study the event-triggered continuous-discrete Kalman filtering problem to control the MSE under a given triggering threshold, where if the mean squared error (MSE) is smaller than this threshold, then an event is triggered to let ...
Yifeng Niu, Yirui Cong, Lizhen Wu
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin   +12 more
wiley   +1 more source

Discrete events: Perspectives from system theory [PDF]

open access: yesQuarterly, 1988
Summary: Mathematical system theory has traditionally been concerned with differential or difference equations. Recently, however, there has been increasing interest of system theorists for `discrete event systems', whose evolution in time is marked by the occurrence of `events' (arrivals of messages or customers, completion of tasks, etc.). This paper
openaire   +5 more sources

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

Improved accumulative-error event-triggered control for discrete-time linear systems with random time delays

open access: yesAIMS Mathematics
A stability problem under event-triggered control for discrete linear systems with random time delays is considered in this paper. First, this paper improves an accumulative error-based event-triggered approach, which can switch the event-triggered ...
Zhi Fu   +3 more
doaj   +1 more source

Detectability of Timed Discrete Event Systems

open access: yesIEEE Access, 2023
This paper introduces T-detectability, which extends detectability to timed discrete event systems within the context of communication networks. We propose network T-detectability to address the challenges posed by observation delays and losses in ...
Chengshi Miao
doaj   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

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