The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
Integrated method for multi-UAV task assignment and trajectory planning with deadlock based on Three-dimensional dubins path. [PDF]
Wu W, Zhang L, Le J, Lu Z.
europepmc +1 more source
Multimaterial 3D Printing of Soft and Stretchable Electronics
A multimaterial resin for two‐photon polymerization integrates PEDOT:PSS and carbon nanotubes to enable direct 3D printing of conductive, insulating, and electroactive microstructures. The hybrid exhibits high conductivity, optical transparency, and stability under strain and pH variation, advancing scalable fabrication of flexible soft electronics and
Omid Dadras‐Toussi +2 more
wiley +1 more source
A Scheduling Method for Maintenance Tasks of Damaged Equipment Based on Digital Twin and Robust Optimization. [PDF]
Jiang M, Jiang T, Guo L, Liu S.
europepmc +1 more source
MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang +5 more
wiley +1 more source
A Nomadic Infrastructure with Hierarchical Block Tracking and Surveillance Resolution in Satellite Networks. [PDF]
Kim M +4 more
europepmc +1 more source
This study presents a hybrid quantum‐classical framework for accurate prediction of protein structures on utility‐level quantum processors. We evaluate the practical application of the Variational Quantum Eigen‐solver (VQE) in protein structure prediction and demonstrate its superiority over state‐of‐the‐art deep learning methods in molecular docking ...
Yuqi Zhang +10 more
wiley +1 more source
A Bi-level optimization method for integrated warehouse design, storage location assignment, and order picking. [PDF]
Moghadam MF +3 more
europepmc +1 more source
OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang +10 more
wiley +1 more source
Genetic Assignment at Different Geographical Levels: A Case Study in a Forest Tree Species (<i>Pinus pinaster</i> Ait.) Using SNP Markers. [PDF]
Olsson S +5 more
europepmc +1 more source

