Results 31 to 40 of about 1,866,263 (284)
A technical overview of metallic parts in hybrid additive manufacturing industry
Journal of Materials Research and Technology, 2022 Additive manufacturing technologies have emerged as the promising alternatives of conventional manufacturing techniques. Conventional manufacturing techniques involves cutting and removal of material by mechanical procedures to achieve final product ...
Mehmet Erdi Korkmaz +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Supremica – An integrated environment for verification, synthesis and simulation of discrete event systems [PDF]
, 2006 An integrated environment, Supremica, for verification, synthesis and simulation of discrete event systems is presented. The basic model in Supremica is finite automata where the transitions have an associated event together with a guard condition and an
\uc5kesson, Knut +8 more
core +1 more source
Research on a Real-Time Control System for Discrete Factories Based on Digital Twin Technology
Applied SciencesGear factories are most typical discrete manufacturing factories. Many gear factories are striving to explore how to achieve intelligent manufacturing in order to improve efficiency and reduce costs.
Shousong Jin +4 more
doaj +1 more source
Complexity, 2018 Discrete manufacturing products are often assembled from multiple parts through a series of discrete processes. How to effectively configure resources in a discrete manufacturing environment is an important research topic worthy of attention. Based on an
Wei Xu, Yinyun Yu
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Systems, 2023 To address issues in discrete manufacturing workshops, such as the difficulty for management personnel to coordinate workshop production and the challenge of visualizing and supervising a massive amount of temporary data, this paper proposes a service ...
Qinglei Zhang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source