Results 41 to 50 of about 715,075 (267)

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Discrete optimization design for cabin-skeleton coupling structure of blended-wing-body underwater glider

Zhongguo Jianchuan Yanjiu, 2021
ObjectivesThe cabin-skeleton coupling structure of a blended-wing-body underwater glider is optimized using a data-driven discrete optimization concept.MethodsFirst, a Kriging-assisted discrete global optimization algorithm (KDGO) is proposed for ...
Huachao DONG, Peng WANG, Yijin ZHANG
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Gene Feature Selection Algorithm Based on Discrete Particle Swarm Optimization and Neighborhood Reduction [PDF]

Jisuanji gongcheng, 2016
Aiming at the problem that the gene feature selection based on discrete Particle Swarm Optimization(PSO) algorithm is easy to fall into local optimal solution,a combined optimization algorithm based on discrete PSO and neighborhood reduction is proposed ...
ZHANG Zhe,SUN Lijun
doaj   +1 more source

On a novel approach for optimizing composite materials panel using surrogate models [PDF]

, 2011
This paper describes an optimization procedure to design thermoplastic composite panels under axial compressive load conditions. Minimum weight is the goal. The panel design is subject to buckling constraints.
Akcay-Perdahcioglu, D., Boer, A. de, De Guido, S., Geijselaers, H.J.M.   +3 more
core   +1 more source

Preferences for post‐traumatic osteoarthritis prevention strategies in individuals with anterior cruciate ligament injury

Arthritis Care &Research, Accepted Article.
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy, Lily Waddell, Adam Easterbrook, Jeffrey N. Katz, Cale Jacobs, Morgan Jones, Faith Selzer, Elena Losina, Liana Fraenkel, Nick Bansback   +9 more
wiley   +1 more source

Sparse Gaussian Processes on Discrete Domains

IEEE Access, 2021
Kernel methods on discrete domains have shown great promise for many challenging data types, for instance, biological sequence data and molecular structure data.
Vincent Fortuin, Gideon Dresdner, Heiko Strathmann, Gunnar Ratsch   +3 more
doaj   +1 more source

Exploring Patients’ Profiles Associated With the Resolution of Acute Calcium Pyrophosphate Arthritis Treated With Colchicine and Prednisone: Post Hoc Analysis of a Randomized Controlled Trial

Arthritis Care &Research, EarlyView.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart, Laurène Norberciak, Pascal Richette, Pierre Robinet, Aurore Pacaud, Gauthier Marchasson, Thibault Rabin, Hélène Luraschi, Pierre Maciejasz, Anne‐France Georgel, Augustin Latourte, Hang‐Korng Ea, Sébastien Ottaviani, Charlotte Jauffret, Vincent Ducoulombier   +14 more
wiley   +1 more source

Customer order scheduling in a permutation flow shop environment

Operations Research Perspectives
Various recent scheduling literature has studied the so called customer order scheduling problem. In this class of scheduling problems, there are multiple customer orders, and each of them consists of several jobs.
Julius Hoffmann, Janis S. Neufeld, Udo Buscher   +2 more
doaj   +1 more source

Hopfield Neural Networks for Online Constrained Parameter Estimation With Time‐Varying Dynamics and Disturbances

International Journal of Adaptive Control and Signal Processing, EarlyView.
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley   +1 more source