Results 31 to 40 of about 4,681,885 (296)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Concentration Properties of Extremal Parameters in Random Discrete Structures [PDF]
Discrete Mathematics & Theoretical Computer Science, 2006 The purpose of this survey is to present recent results concerning concentration properties of extremal parameters of random discrete structures. A main emphasis is placed on the height and maximum degree of several kinds of random trees. We also provide
Michael Drmota
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
MAIN DIRECTIONS IN GEOMETRIC SHAPING OF REGULAR DISCRETE STRUCTURES IN DESIGN
Архитектон, 2021 The article expands on some important aspects in the geometric shaping of regular discrete structures in different areas of design and architecture and outlines main promising directions for their development.
Korotich Andrey V.
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Differentiable Relaxations for Discrete Structures in Machine Learning
, 2023 Discrete structures and operations are prevalent in many machine learning applications, but their non-differentiable nature poses challenges for gradient-based optimization.
Mashrin Srivastava
core +1 more source
SOME MORPHOLOGICAL ASPECTS OF FORM IN REGULAR DISCRETE STRUCTURES IN DESIGN
Архитектон, 2021 Some aspects of geometric form generation in regular discrete structures for different spheres of design and architecture are elaborated and the main promising directions/trends in their development are identified.
Korotich Andrey V.
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Propagation and Reflection In Discrete-Space-Discrete-Time Structures
, 1984 We describe the essential mathematics that are to be invoked to arrive at a coherent description of energy conservation, propagation and reflection in discrete-space-discrete-time structures.
core +1 more source
Teaching discrete structures [PDF]
Proceedings of the 42nd ACM technical symposium on Computer science education, 2011 This survey paper reviews a large sample of publications on the teaching of discrete structures and discrete mathematics in computer science curricula. The approach is systematic, in that a structured search of electronic resources has been conducted, and the results are presented and quantitatively analyzed.
James F. Power +2 more
openaire +2 more sources