Results 41 to 50 of about 468,243 (267)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
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Oscillators: Phenomenological mappings and analogies: Second part: Structural analogy and chains [PDF]
Scientific Technical Review, 2015 New analytical and numerical results of dynamics for both linear and nonlinear system with two degrees of freedom are presented. For the mechanical chain system with two degrees of freedom, oscillations are investigated analytically and numerically with ...
Hedrih-Stevanović Katica +4 more
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Some new soliton solutions of a semi-discrete fractional complex coupled dispersionless system
Scientific Reports, 2023 In this paper, a semi-discrete fractional derivative complex coupled dispersionless system is proposed. The properties of M-fractional derivative are utilized to convert discrete M-fractional derivative system to a classical discrete differential system.
A. H. Abdel Kader +3 more
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Discrete Pseudo-SINR-Balancing Nonlinear Recurrent System
Discrete Dynamics in Nature and Society, 2013 Being inspired by the Hopfield neural networks (Hopfield (1982) and Hopfield and Tank (1985)) and the nonlinear sigmoid power control algorithm for cellular radio systems in Uykan and Koivo (2004), in this paper, we present a novel discrete recurrent ...
Zekeriya Uykan
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
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General solutions of weakly delayed discrete systems in 3D
Advances in Nonlinear AnalysisDiscrete systems x(k+1)=Ax(k)+Bx(k−m)x\left(k+1)=Ax\left(k)+Bx\left(k-m), k=0,1,…k=0,1,\ldots \hspace{0.33em} are analyzed, where mm is a fixed positive integer, AA, BB are constant 3 by 3 matrices and x:{−m,−m+1,…}→R3x:\left\{-m,-m+1,\ldots \right\}\to {
Diblík Josef +3 more
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Robust Control of Nonlinear Discrete Systems With Perturbations Based on Estimated State Feedback
IEEE AccessNonlinear discrete control system theory, which is increasingly garnering attention, has important applications in computer control theory. In this study, the robust control problem of nonlinear discrete systems with perturbations is investigated.
Yanxiu Sun, Jia Long
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Journal of Engineering Technology and Applied PhysicsThis study investigates the soliton propagation in a one-dimensional discrete system characterized by the Discrete Nonlinear Schrödinger Equation (DNLSE).
Nor Amirah Busul Aklan +2 more
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