Results 61 to 70 of about 468,243 (267)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Survey of modeling methods in cyber-physical system

open access: yesTongxin xuebao, 2016
Cyber-physical system(CPS)not only contains the discrete calculation process and network communication,but also involves in the handling of continuous physical events.Based on discrete system and continuous system,some existing modeling theories and ...
Ren-fa LI   +4 more
doaj  

Discrete Dubrovin equations and separation of variables for discrete systems [PDF]

open access: yesChaos, Solitons & Fractals, 2000
Talk presented at the Intl. Conf. on ``Integrability and Chaos in Discrete Systems'', July 2-6, 1997, to appear in: Chaos, Solitons and Fractals, ed. F. Lambert, (Pergamon Press)
openaire   +3 more sources

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Service chain caching and task offloading in two-tier UAV-assisted vehicular edge computing networks: An attention-DRL method

open access: yesDigital Communications and Networks
Unmanned Aerial Vehicle (UAV)-assisted Vehicular Edge Computing Networks (VECNs) have emerged as a promising solution to enhance service quality for ground vehicle users.
Fengyan Wu   +4 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Bifurcation in a Discrete Competition System

open access: yesDiscrete Dynamics in Nature and Society, 2014
A new difference system is induced from a differential competition system by different discrete methods. We give theoretical analysis for local bifurcation of the fixed points and derive the conditions under which the local bifurcations such as flip ...
Li Xu   +5 more
doaj   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

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