Results 41 to 50 of about 32,280 (249)

Discrete Spacings

open access: yesStatistica Neerlandica, 2003
Consider a string of n positions, i.e. a discrete string of length n. Units of length k are placed at random on this string in such a way that they do not overlap, and as often as possible, i.e. until all spacings between neighboring units have length less than k. When centered and scaled by n−1/2 the resulting numbers of spacings of length 1, 2,…, k−1
Klaassen, C.A.J., Runnenburg, J.T.
openaire   +6 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Finite Element Method: An Overview

open access: yesWalailak Journal of Science and Technology, 2013
The finite element method (FEM) is a numerical analysis technique for obtaining approximate solutions to a wide variety of engineering problems. A finite element model of a problem gives a piecewise approximation to the governing equations.
Vishal JAGOTA   +2 more
doaj   +1 more source

Discrete Takagi-Sugeno Fuzzy Models Applied to Control the Knee Joint Movement of Paraplegic Patients

open access: yesIEEE Access, 2020
In this manuscript, a method for designing Takagi-Sugeno (T-S) fuzzy discrete-time regulators based on linear matrix inequalities (LMIs) is proposed to control the variation of the knee joint angle movement of paraplegic patients through electrical ...
Ruberlei Gaino   +6 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Modelling Interaction Effects by Using Extended WOE Variables with Applications to Credit Scoring

open access: yesMathematics, 2021
The term credit scoring refers to the application of formal statistical tools to support or automate loan-issuing decision-making processes. One of the most extended methodologies for credit scoring include fitting logistic regression models by using WOE
Carlos Giner-Baixauli   +3 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

MORPHOLOGICAL SAMPLING OF CLOSED SETS

open access: yesImage Analysis and Stereology, 2011
We briefiy survey the standard morphological approach (Heijmans, 1994) to the sampling (or discretization) of sets. Then we summarize the main results of our metric theory of sampling (Ronse and Tajine, 2000; 2001; 2002; Tajine and Ronse, 2002), which ...
Christian Ronse, Mohamed Tajine
doaj   +1 more source

Station Arrangement Optimization of Photoelectric Theodolites Based on Efficient Traversing Discrete Points

open access: yesPhotonics, 2023
Station arrangement optimization of photoelectric theodolites in shooting ranges presents a non-convex and non-linear problem, and the method required to seek the global optimal solution remains an open question.
Zhenyu Miao   +4 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

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