Results 91 to 100 of about 580,173 (268)

TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

open access: yesAdvanced Science, EarlyView.
A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du   +17 more
wiley   +1 more source

DISCRIMINANT STEPWISE PROCEDURE

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2014
Stepwise procedure is now probably the most popular tool for automatic feature selection. In the most cases it represents model selection approach which evaluates various feature subsets (so called wrapper). In fact it is heuristic search technique which
Mariusz Kubus
doaj  

METHODS FOR TESTING DISCRIMINANT VALIDITY [PDF]

open access: yesManagement & Marketing, 2011
The study presents three methods which can be used to assess discriminant validity for multi-item scales. Q-sorting is presented as a method that can be used in early stages of research, being more exploratory, while the chi-square difference test and ...
Adriana ZAIŢ, Patricea Elena BERTEA
doaj  

Low-dimensional Singularities with Free Divisors as Discriminants

open access: yes, 2006
We present versal complex analytic families, over a smooth base and of fibre dimension zero, one, or two, where the discriminant constitutes a free divisor.
Bothmer, Hans-Christian Graf v.   +2 more
core  

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

open access: yesAdvanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying   +8 more
wiley   +1 more source

Discriminant analysis of multivariate spatial regressions

open access: yesLietuvos Matematikos Rinkinys, 2001
There is not abstract.
Kęstutis Dučinskas, Jūratė Šaltytė
doaj   +1 more source

Localized Linear Discriminant Analysis [PDF]

open access: yes
Despite its age, the Linear Discriminant Analysis performs well even in situations where the underlying premises like normally distributed data with constant covariance matrices over all classes are not met.
Czogiel, Irina   +3 more
core  

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

open access: yesAdvanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta   +14 more
wiley   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

open access: yesAdvanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li   +12 more
wiley   +1 more source

Mixed discriminants

open access: yesMathematische Zeitschrift, 2012
The mixed discriminant of n Laurent polynomials in n variables is the irreducible polynomial in the coefficients which vanishes whenever two of the roots coincide. The Cayley trick expresses the mixed discriminant as an A-discriminant. We show that the degree of the mixed discriminant is a piecewise linear function in the Plucker coordinates of a mixed
Cattani, Eduardo   +4 more
openaire   +3 more sources

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