Results 91 to 100 of about 584,742 (263)

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

Advanced Science, EarlyView.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu, Rongrong Wu, Zhicheng Liu, Hongyu Yan, Huan Zhang, Yuanyi Zheng, Xiaojun Cai   +6 more
wiley   +1 more source

METHODS FOR TESTING DISCRIMINANT VALIDITY [PDF]

Management & Marketing, 2011
The study presents three methods which can be used to assess discriminant validity for multi-item scales. Q-sorting is presented as a method that can be used in early stages of research, being more exploratory, while the chi-square difference test and ...
Adriana ZAIŢ, Patricea Elena BERTEA
doaj  

Localized Linear Discriminant Analysis [PDF]

Despite its age, the Linear Discriminant Analysis performs well even in situations where the underlying premises like normally distributed data with constant covariance matrices over all classes are not met.
Czogiel, Irina, Luebke, Karsten, Weihs, Claus, Zentgraf, Marc   +3 more
core  

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Fuzzy Discriminant Analysis with Application

المجلة العراقية للعلوم الاحصائية
In the current research, two methods of data classification were used, namely; the Linear Discriminant analysis (LDA) and the Fuzzy Discriminant Analysis (FDA).
Rafal Talal Saadi, Alla A. Hamoodat
doaj   +1 more source

Statistical classification techniques for engineering and climatic data samples [PDF]

Fisher's sample linear discriminant function is modified through an appropriate alteration of the common sample variance-covariance matrix. The alteration consists of adding nonnegative values to the eigenvalues of the sample variance covariance matrix ...
Shipman, J. R., Temple, E. C.
core   +1 more source

Mixed discriminants

Mathematische Zeitschrift, 2012
The mixed discriminant of n Laurent polynomials in n variables is the irreducible polynomial in the coefficients which vanishes whenever two of the roots coincide. The Cayley trick expresses the mixed discriminant as an A-discriminant. We show that the degree of the mixed discriminant is a piecewise linear function in the Plucker coordinates of a mixed
Cattani, Eduardo, Cueto, Maria Angelica, Dickenstein, Alicia, Rocco, Sandra Di, Strumfels, Bernd   +4 more
openaire   +3 more sources

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

Advanced Science, EarlyView.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu, Mei Liu, Changxing Gao, Cheng Zhao, Feijie Zhao, Shuqing Dong, Bo Zhang, Qianmei Liu, Wenqian Zhang, Ming Zhao, Qianjin Lu   +10 more
wiley   +1 more source

Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol‐Induced Intestinal Injury via Microbiota‐Dependent and ‐Independent AHR Activation

Advanced Science, EarlyView.
Glucuronolactone (GLU) as a natural metabolite of glucose, increases Lactobacillus amylovorus abundance and luminal IAA level to activate AHR signaling. In addition, GLU itself can directly elevate AHR signaling activity independently of microbiota and IAA.
Chenbin Cui, Beibei Zhang, Jiaxi Tang, Jing Hou, Yueqin Qiu, Kaiguo Gao, Li Wang, Zongyong Jiang, Xuefen Yang   +8 more
wiley   +1 more source

FomA‐Containing Outer Membrane Vesicles of Fusobacterium Nucleatum Facilitate Bladder Cancer Lymphatic Metastasis via IL‐6‐Dependent M2b Macrophage Polarization

Advanced Science, EarlyView.
Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan, Weijia Li, Wenxue Huang, Jilin Wu, Yao Yu, Yiyao Huang, Lin Yang, Ming Xie, Qishen Yang, Jun Zheng, Yuexuan Zhu, Qi Sun, Biao Li, Leqian Li, Zongwei Wang, Jie Zhao, Peng Wu, Bisheng Cheng   +17 more
wiley   +1 more source