Results 51 to 60 of about 1,172,950 (315)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
The Geometry of Nonlinear Embeddings in Kernel Discriminant Analysis [PDF]
, 2020 Fisher's linear discriminant analysis is a classical method for classification, yet it is limited to capturing linear features only. Kernel discriminant analysis as an extension is known to successfully alleviate the limitation through a nonlinear feature mapping.
arxiv +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Racial Discrimination in the Sharing Economy: Evidence from a Field Experiment
, 2016 In an experiment on Airbnb, we find that applications from guests with distinctively African American names are 16 percent less likely to be accepted relative to identical guests with distinctively white names.
Benjamin Edelman +2 more
semanticscholar +1 more source
Discrimination of Optical Coherent States using a Photon Number Resolving Detector [PDF]
, 2009 The discrimination of non-orthogonal quantum states with reduced or without errors is a fundamental task in quantum measurement theory. In this work, we investigate a quantum measurement strategy capable of discriminating two coherent states probabilistically with significantly smaller error probabilities than can be obtained using non-probabilistic ...
arxiv +1 more source
Pauvreté, Genre et inégalités de droit au Maroc
Revue des Etudes Multidisciplinaires en Sciences Economiques et Sociales, 2020 La pauvreté se traduit essentiellement en un état de manque, un manque de ressources financières mettant la personne dans une situation de besoins qui ne peuvent se satisfaire soit partiellement, soit totalement.
Rym CHERKAOUI, Latifa EL MAHDATI
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Black Americans have a higher risk of hypertension compared with White Americans. Perceived discrimination is a plausible explanation for these health disparities.
Allana T. Forde +4 more
doaj +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Discrimination in the Age of Algorithms [PDF]
Social Science Research Network, 2018 The law forbids discrimination. But the ambiguity of human decision-making often makes it extraordinarily hard for the legal system to know whether anyone has actually discriminated.
J. Kleinberg +3 more
semanticscholar +1 more source