Results 91 to 100 of about 767,513 (309)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Düzce Üniversitesi Tıp Fakültesi Öğrencilerine Uygulanan Sınavlarda Soruların Geçerlik ve Güvenirlik Analizi

open access: yesDüzce Tıp Fakültesi Dergisi, 2018
Amaç: Bu araştırmanın amacı Düzce Üniversitesi Tıp Fakültesi Dönem I, Dönem II ve Dönem III öğrencilerine uygulanan sınav sorularının geçerlik ve güvenirlik analizlerini yapmaktır.Gereç ve Yöntemler: Düzce Üniversitesi Tıp Fakültesi Öğrenci İşlerinden ...
Handan ANKARALI   +3 more
doaj  

Dealing with a potential bias in estimating the share of discriminated women [PDF]

open access: yes, 2012
The Blinder-Oaxaca [1, 6] decomposition neglects any distributional issues of discrimination. Instead, Jenkins [5] has argued the importance of a distributional approach in evaluating wage discrimination, focusing on the entire distribution of ...
GIAIMO, Rosa, LO MAGNO, Giovanni Luca
core  

Euler-Bessel and Euler-Fourier Transforms

open access: yes, 2010
We consider a topological integral transform of Bessel (concentric isospectral sets) type and Fourier (hyperplane isospectral sets) type, using the Euler characteristic as a measure.
Baryshnikov Y   +9 more
core   +2 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Evaluation of Discrimination Indices Validity for Screening of β-Thalassemia Trait [PDF]

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2009
Background and Objectives: β-thalassemia trait (β-TT) and iron deficiency anemia (IDA) are the most common forms of microcytic anemia. Screening of β-thalassemia trait is important for medical counseling before marriage and preventing β-thalassemia major
Ahmadi A.   +4 more
doaj   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Prediction Ability of Charlson, Elixhauser, and Rx-Risk Comorbidity Indices for Mortality in Patients with Hip Fracture. A Danish Population-Based Cohort Study from 2014 – 2018

open access: yesClinical Epidemiology, 2022
Jeppe Damgren Vesterager, Morten Madsen, Thomas Johannesson Hjelholt, Pia Kjær Kristensen, Alma Becic Pedersen Department of Clinical Epidemiology, Aarhus University Hospital and Department of Clinical Medicine, Aarhus University, Aarhus ...
Vesterager JD   +4 more
doaj  

More or less unequal? Evidence on the pay of men and women from the British Birth Cohort Studies [PDF]

open access: yes, 2006
Gender pay differences are not merely a problem for women returning to work and part-time employees, but also for those in full-time, continuous careers.
Dolton, Peter   +2 more
core   +3 more sources

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

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