Results 131 to 140 of about 5,142,656 (331)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen   +6 more
wiley   +1 more source

Social Justice in the EU – Index Report 2017 Social Inclusion Monitor Europe. Bertelsmann Stiftung Social Inclusion Monitor Europe 2017 [PDF]

open access: yes, 2017
1. Europe is recovering not only economically, but also in the domain of social justice After years of downward movement, an upward trend in the domain of social justice is evident in the broad majority of EU member states.
Christof Schiller, Christof Schiller   +3 more
core  

Evaluating Pricing Strategy Using e-Commerce Data: Evidence and Estimation Challenges

open access: yes, 2006
As Internet-based commerce becomes increasingly widespread, large data sets about the demand for and pricing of a wide variety of products become available.
Ghose, Anindya, Sundararajan, Arun
core   +2 more sources

Evaluation of Validity of Computer Based Test Items in NOUN

open access: yesWest African Journal of Open and Flexible Learning, 2018
Multiple Choice Items (MCI) are one of the most commonly used Computer Based Assessment (CBA) instrument for assessment of students in educational settings especially in Open and Distance Learning (ODL) with large class sizes.
Charity Akuadi Okonkwo
doaj  

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting   +12 more
wiley   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic   +6 more
wiley   +1 more source

HAVE ECONOMIC REFORMS PAID-OFF? GENDER OCCUPATIONAL INEQUALITY IN THE NEW MILLENNIUM IN EGYPT [PDF]

open access: yes, 2008
This study considers the impact of over a decade of structural adjustment policies in Egypt on gender wage and occupational inequality. Using newly released Labor Force Sample Surveys (LFSS) for the years 2000-2004, a slight drop in public sector ...
El-Hamidi, Fatma, Said, Mona
core  

Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams   +14 more
wiley   +1 more source

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