Results 131 to 140 of about 19,607,477 (309)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Mental health and quality of life in COVID‐19 survivors: A needed discussion [PDF]
, 2021 Sophia De Moraes De Medeiros +3 more
openalex +1 more source
A Comparison of Cointegration & Tracking Error Models for Mutual Funds & Hedge Funds [PDF]
We present a detailed study of portfolio optimisation based on cointegration, a statistical tool that here exploits a long-run equilibrium relationship between stock prices and an index price.
Anca Dimitriu, Carol Alexander
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Effectiveness of Britain's Financial Service Authority: An Economic Analysis [PDF]
Sweeping regulatory reforms in Britain resulted in the formation of the Financial Services Authority (FSA). Because greater transparency of information is a major objective for this Act, shifting from one information system to another has re-distributive
Colin Beardsley, John R. O'Brien
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Application-Based Financial Risk Aggregation methods [PDF]
Financial risks are usually analysed by type and by activity using different assumptions and methodologies as may seem appropriate in each case. This approach makes it very difficult to ascertain the degree of diversification between various activities ...
Jacques Pezier
core