Anatomical Resection Improves Disease-Free Survival After Lung Metastasectomy of Colorectal Cancer
Cancer Management and Research, 2021 Tianyu Liu,1,* Wenju Chang,1,2,* Hao Wang,3,* Qi Lin,1,2,* Ye Wei,1,2 Wentao Tang,1 Yu Liu,1 Yijiao Chen,1 Zhengchuan Niu,1 Yudong Jiang,1 Li Ren,1,2 Jianmin Xu1,2 1Colorectal Cancer Center, Department of General Surgery, Zhongshan ...
Liu T +11 more
doaj
Erlotinib in patients with previously irradiated, recurrent brain metastases from non-small cell lung cancer: Two case reports [PDF]
, 2008 Background: With the current improvements in primary lung care, the long-term control of brain metastases becomes a clinical challenge. No established therapeutic approaches exist for cranial relapse after response to previous radiotherapy and systemic ...
Abrey LE +13 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Frontiers in Oncology, 2015 Purpose: We aimed to externally validate the association of 2- and 3-year disease-free survival with 5-year overall survival in patients treated with radical cystectomy for urothelial carcinoma of the bladder.
Hyung Suk eKim +4 more
doaj +1 more source
Does delaying curative surgery for colorectal cancer influence long-term disease-free survival? A cohort study [PDF]
, 2021 Stephanie García‐Botello +6 more
openalex +1 more source
Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer. [PDF]
, 2009 CONTEXT: The established relationship between lymph node metastasis and prognosis in colorectal cancer suggests that recurrence in 25% of patients with lymph nodes free of tumor cells by histopathology (pN0) reflects the presence of occult metastases ...
Barkun, Alan +8 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Journal of Clinical and Diagnostic ResearchIntroduction: Vaginal malignancy is a rare gynaecological malignancy, and authors know little about its survival and prognostic factors. The management of vaginal malignancies is largely determined by factors such as histological type, tumor size ...
Ramani Gangadharan Ashitha +3 more
doaj +1 more source
PLoS ONE, 2014 BackgroundPrevious studies suggested that diabetes mellitus was associated with cancer risk and prognosis, but studies investigating the relationship between diabetes mellitus and survival in patients with hepatocellular carcinoma (HCC) reported ...
Yan-Gang Wang +5 more
doaj +1 more source
Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy [PDF]
, 2013 Uracil in DNA is an important cause of mutagenesis. SMUG1 is a uracil DNA glycosylase that removes uracil through base excision repair. SMUG1 also processes radiation induced oxidative base damage as well as 5-fluorouracil incorporated into DNA during
Abdel-Fatah, TMA +9 more
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