Results 131 to 140 of about 1,967,846 (356)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Survival after initial lung metastasectomy for metastatic colorectal cancer in the modern chemotherapeutic era

BMC Surgery, 2017
Background A clear survival benefit has been reported for lung metastasectomy for colorectal cancer, and several clinicopathological prognostic factors have been proposed in the past.
Shintaro Yokoyama, Masahiro Mitsuoka, Tetsushi Kinugasa, Toshihiro Hashiguchi, Ryoichi Matsumoto, Daigo Murakami, Tatsuya Nishi, Koichi Yoshiyama, Masaki Kashihara, Shinzo Takamori, Yoshito Akagi   +10 more
doaj   +1 more source

A five-year disease-free survival after combined hepatectomy and radiofrequency ablation of large hepatocellular carcinoma adjacent to vena cava [PDF]

, 2008
Alexander Julianov, Ivan Rachkov, Anatoli Karashmalakov   +2 more
openalex   +1 more source

Clinical Characteristics and Transplant-Free Survival Across the Spectrum of Pulmonary Vascular Disease

, 2022
Anna R. Hemnes, Jane A. Leopold, Milena Radeva, Gerald J. Beck, Aiden Abidov, Micheala A. Aldred, John Barnard, Erika B. Rosenzweig, Barry A. Borlaug, Wendy K. Chung, Suzy Comhair, Ankit A. Desai, Hilary M. DuBrock, Serpil C. Erzurum, J. Emanuel Finet, Robert P. Frantz, Joe G. N. Garcia, Mark W. Geraci, Michael P. Gray, Gabriele Grünig, Paul M. Hassoun, Kristin B. Highland, Nicholas S. Hill, Bo Hu, Deborah Kwon, Miriam Jacob, Christine Jellis, A. Brett Larive, Jason K. Lempel, Bradley A. Maron, Stephen C. Mathai, Kevin McCarthy, Reena Mehra, R Nawabit, John H. Newman, Mitchell A. Olman, Margaret M. Park, José Ramos, Rahul D. Renapurkar, Franz Rischard, Susan G. Sherer, W.H. Wilson Tang, James D. Thomas, Rebecca Vanderpool, Aaron B. Waxman, Jennifer Wilcox, Jason X.‐J. Yuan, Evelyn M. Horn   +47 more
openalex   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

A novel inflammation-related prognostic biomarker for predicting the disease-free survival of patients with colorectal cancer [PDF]

, 2022
Xiaoling Cai, Fa Chen, Lisheng Liang, Weizhong Jiang, Xing Liu, Dong Wang, Yunli Wu, Jinyan Chen, Guoxian Guan, Xian‐E Peng   +9 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Associations of Complete Blood Count Parameters with Disease-Free Survival in Right- and Left-Sided Colorectal Cancer Patients [PDF]

, 2022
Alhasan Alsalman, Mohammad A. Al-Mterin, Ala Abu-Dayeh, Ferial Alloush, Khaled Murshed, Eyad Elkord   +5 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source