Results 31 to 40 of about 1,967,846 (356)

High IKKα expression is associated with reduced time to recurrence and cancer specific survival in oestrogen receptor (ER)-positive breast cancer [PDF]

, 2017
The aim of our study was to examine the relationship between tumour IKKα expression and breast cancer recurrence and survival. Immunohistochemistry was employed in a discovery and a validation tissue microarray to assess the association of tumour IKKα ...
Bennett, Lindsay, Edwards, Joanne, Horgan, Paul G., Mallon, Elizabeth A., McCall, Pamela, McMillan, Donald C., Paul, Andrew, Quinn, Jean   +7 more
core   +2 more sources

Adjuvant treatment with tumor-targeting Salmonella typhimurium A1-R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model. [PDF]

, 2015
Colon cancer liver metastasis is often the lethal aspect of this disease. Well-isolated metastases are candidates for surgical resection, but recurrence is common. Better adjuvant treatment is therefore needed to reduce or prevent recurrence.
Bouvet, Michael, Chishima, Takashi, Endo, Itaru, Hiroshima, Yukihiko, Hoffman, Robert M, Murakami, Takashi, Tanaka, Kuniya, Zhang, Yong, Zhao, Ming   +8 more
core   +2 more sources

Long-term outcome after a treosulfan-based conditioning regimen for patients with acute myeloid leukemia: A report from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation [PDF]

, 2017
BACKGROUND: Allogeneic hematopoietic cell transplantation (HCT) is a curative therapy for patients with acute myeloid leukemia (AML). However, post-HCT relapse and regimen-related toxicity remain significant barriers to long-term survival.
Al Mumma, Baron, Boztug, Boztug, Bredeson, Burroughs, Carreras, Casper, Casper, Cieri, Copelan, Dalle, Danylesko, Fichtner, Galaup, Glowka, Gupta, Gyurkocza, Kroger, Kroger, Majhail, Meinhardt, Munkelt, Nagler, Nagler, Palmer, Pel, Richardson, Rizzo, Savani, Savani, Scheulen, Schmidmaier, Schmitt, Sengsayadeth, Sengsayadeth, Shimoni, Shimoni, Slatter, ten Brink, Wachowiak, Williams   +41 more
core   +1 more source

A multicentre case control study on complicated coeliac disease: two different patterns of natural history, two different prognoses. [PDF]

, 2014
Background: Coeliac disease is a common enteropathy characterized by an increased mortality mainly due to its complications. The natural history of complicated coeliac disease is characterised by two different types of course: patients with a new ...
Ambrosiano, G., Andrealli, A., Astegiano, M., Biagi, F., Caio, G., Carroccio, A., Ciacci, C., Ciccocioppo, R., Corazza, G., D'Odorico, A., de Pretis, G., De Vitis, I., Ferretti, F., Gasbarrini, A., Gobbi, P., M. a. r. c. h. e. s. e., A., Mansueto, P., Meggio, A., Neri, M., Piscaglia, A., Schiepatti, A., Segato, S., Volta, U., Zingone, F.   +23 more
core   +1 more source

GRFS and CRFS in alternative donor hematopoietic cell transplantation for pediatric patients with acute leukemia. [PDF]

, 2019
We report graft-versus-host disease (GVHD)-free relapse-free survival (GRFS) (a composite end point of survival without grade III-IV acute GVHD [aGVHD], systemic therapy-requiring chronic GVHD [cGVHD], or relapse) and cGVHD-free relapse-free survival ...
Abdel-Azim, Hisham, Ahmed, Ibrahim, Aljurf, Mahmoud, Alousi, Amin M., Arora, Mukta, Askar, Medhat, Auletta, Jeffery J., Bhatt, Vijaya, Bredeson, Christopher, Chhabra, Saurabh, Couriel, Daniel R., Diaz, Miguel Angel, Gadalla, Shahinaz, Gajewski, James, Gale, Robert Peter, Gergis, Usama, Hematti, Peiman, Hemmer, Michael T., Hildebrandt, Gerhard C., Holtan, Shernan G, Inamoto, Yoshihiro, Khandelwal, Pooja, Kitko, Carrie, MacMillan, Margaret L., Majhail, Navneet, Marks, David I., Mehta, Parinda, Mehta, Rohtesh S., Nishihori, Taiga, Olsson, Richard F., Pawarode, Attaphol, Pidala, Joseph, Prestidge, Tim, Qayed, Muna, Rangarajan, Hemalatha, Ringden, Olle, Saad, Ayman, Savani, Bipin N., Schultz, Kirk R., Seo, Sachiko, Shah, Ami, Shah, Niketa, Solh, Melhem, Spellman, Stephen R., Spitzer, Thomas, Szer, Jeffrey, Teshima, Takanori, Verdonck, Leo F, Wagner, John, Wang, Tao, Weisdorf, Daniel J., Williams, Kirsten M., Wirk, Baldeep, Yared, Jean A.   +53 more
core   +2 more sources

Measuring Disease-Free Survival and Cancer Relapse Using Medicare Claims From CALGB Breast Cancer Trial Participants (Companion to 9344) [PDF]

, 2014
To determine the accuracy with which Medicare claims data measure disease-free survival in elderly Medicare beneficiaries with cancer, we performed a criterion validation study. We merged gold-standard clinical trial data of 45 elderly patients with node-
Christakis, Nicholas A., Earle, Craig C., Henderson, I. Craig, Herndon, James E., Lamont, Elizabeth B., Schilsky, Richard L., Weeks, Jane C.   +6 more
core   +1 more source

HERMIONE: a randomized Phase 2 trial of MM-302 plus trastuzumab versus chemotherapy of physician's choice plus trastuzumab in patients with previously treated, anthracycline-naïve, HER2-positive, locally advanced/metastatic breast cancer. [PDF]

, 2016
BackgroundHuman epidermal growth factor receptor 2 (HER2)-positive breast cancer is a particularly aggressive form of the disease, and ultimately progresses in patients with metastases on standard therapies.
Cortes, Javier, Hurvitz, Sara A, Krop, Ian E, Miller, Kathy, Molnar, Istvan, Reynolds, Joseph G, Riahi, Kaveh, Tripathy, Debu, Verma, Sunil, Wickham, Thomas J, Yardley, Denise A   +10 more
core   +2 more sources

Resection of the liver for colorectal carcinoma metastases - A multi-institutional study of long-term survivors [PDF]

, 1988
In this review of a collected series of patients undergoing hepatic resection for colorectal metastases, 100 patients were found to have survived greater than five years from the time of resection. Of these 100 long-term survivors, 71 remain disease-free
Abrams, J, Adson, MA, Al-Jurf, A, Aldrete, JS, Blumgart, LH, Bradpiece, H, Cady, B, Connolly, DP, Coppa, GF, Daly, JM, Dillon, D, Enker, WE, Fitzherbert, D, Fortner, JG, Foster, JH, Happ, R, Harbora, D, Hardy, TG, Herrera, L, Hobbs, KEF, Hodgson, WJ, Hohenberger, P, Howard, T, Hughes, KS, Ilstrup, DM, Iwatsuki, S, Lee, E, Li, MKW, Lim, C, Longmire, WP, Maclean, BJ, McDermott, W, McPherson, TA, Nims, T, O'Toole, K, Oster, M, Petrelli, NJ, Ramming, KP, Remine, SG, Ripepi, P, Rosenstein, RB, Rossi, RL, Schlag, P, Smith, W, Songhorabodi, S, Starzl, T, Steele, G, Sugarbaker, PH, Urist, M, Villella, E   +49 more
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Disease-free survival as a surrogate endpoint for overall survival in adjuvant trials of pancreatic cancer: a meta-analysis of 20 randomized controlled trials

BMC Cancer, 2020
Background We aimed to assess whether disease-free survival (DFS) could serve as a reliable surrogate endpoint for overall survival (OS) in adjuvant trials of pancreatic cancer.
Run-Cong Nie, Xue-Bin Zou, Shu-Qiang Yuan, Ying-Bo Chen, Shi Chen, Yong-Ming Chen, Guo-Ming Chen, Xiao-Jiang Chen, Tian-Qi Luo, Shu-Man Li, Jin-Ling Duan, Yun Wang, Yuan-Fang Li   +12 more
doaj   +1 more source

A Prospective Study of Long-term Outcomes in Female Patients with Nonalcoholic Steatohepatitis Using Age- and Body Mass Index-matched Cohorts [PDF]

, 2013
In patients with nonalcoholic steatohepatitis (NASH), the prevalence of cirrhosis is higher among women than men, and hepatocellular carcinoma (HCC) develops mainly in the cirrhotic stage among women.
Hashizume, Hiroaki, Horiguchi, Norio, Kakizaki, Satoru, Mori, Masatomo, Sato, Ken, Yamazaki, Yuichi   +5 more
core   +1 more source