Results 41 to 50 of about 1,039,355 (265)

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

High expression of metabolic enzyme PFKFB4 is associated with poor prognosis of operable breast cancer

Cancer Cell International, 2019
Background Enhanced glycolysis in tumors, known as the Warburg effect, provides the metabolic basis of enhanced cancer cell proliferation and metastasis.
Ling Yao, Lei Wang, Zhi-Gang Cao, Xin Hu, Zhi-Ming Shao   +4 more
doaj   +1 more source

The relationship between diabetes and colorectal cancer prognosis: A meta-analysis based on the cohort studies. [PDF]

PLoS ONE, 2017
Though a meta-analysis reported the effect of diabetes on colorectal prognosis in 2013, a series of large-scale long-term cohort studies has comprehensively reported the outcome effect estimates on the relationship between diabetes and colorectal ...
Bo Zhu, Xiaomei Wu, Bo Wu, Dan Pei, Lu Zhang, Lixuan Wei   +5 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Singe intraoperative instillation of chemotherapy during radical cystectomy for bladder cancer: Oncological outcome and survival predictors

Cancer Medicine, 2023
Purpose To clarify the necessity and effect of a single intraoperative instillation of chemotherapy during radical cystectomy. Methods Patients who underwent radical cystectomy for bladder cancer between January 2013 and April 2019 were retrospectively ...
Jingtian Yang, Kaiwen Li, Yishan Zhang, Jintao Hu, Hao Liu, Wen Dong, Hai Huang, Tianxin Lin, Jian Huang, Wang He   +9 more
doaj   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Prognostic Significance of Postoperative and Post-Adjuvant Circulating Tumor DNA in Resected Colon Cancer: A Systematic Review and Meta-Analysis

Journal of Clinical Question
Background: Circulating tumor DNA (ctDNA) is a promising biomarker for detecting minimal residual disease in colon cancer. We performed a systematic review and meta-analysis to assess the prognostic value of postoperative and post-adjuvant chemotherapy ...
En Wang, Maho Sasaki, Daisuke Nagashima, Yushi Fujiwara, Taigo Tokuhara   +4 more
doaj   +1 more source

Survival Outcomes of Patients with Locally Advanced Breast Cancer after Neoadjuvant Systemic Therapy in St. Luke’s Medical Center

Asian Pacific Journal of Cancer Care, 2023
Background: In locally-advanced breast cancers (LABC), the previous primary goal of neoadjuvant systemic therapy was to improve resectability and achieve better margins.
Cristina G. Domingo, Fritz Lorenz E. Ortega, Mark James Arce, Mel Valerie B. Cruz-Ordinario, Agnes E. Gorospe, Carlos Dy   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Favorable Long-Term Outcome in Male Breast Cancer

European Journal of Breast Health, 2018
Objective: Male breast cancer (MBC) is a rare type of cancer in the breast cancer series and in the male population. Data is usually extrapolated from female breast cancer (FBC) studies. We aim to study the clinicopathological characteristics and outcome
Enver Özkurt, Mustafa Tükenmez, Ravza Yılmaz, Neslihan Cabioğlu, Mahmut Müslümanoğlu, Ahmet Said Dinççağ, Abdullah İğci, Vahit Özmen   +7 more
doaj   +1 more source