Results 51 to 60 of about 1,039,355 (265)

The Search for an Ideal Definitive Treatment of Sinonasal Squamous Cell Carcinoma With Orbit Invasion [PDF]

Clinical and Experimental Otorhinolaryngology
Objectives. Sinonasal squamous cell carcinoma (SqCC) often invades the orbit. The treatment approach for sinonasal cancer that has spread to the orbit varies across medical centers and depends on the extent of the invasion.
Seung Cheol Han, Jeon Seong, Sung-Woo Cho, Hyun-Jik Kim, Jeong-Whun Kim, Dong-Young Kim, Chae-Seo Rhee, Tae-Bin Won   +7 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Disease-free survival in patients with non-metastatic breast cancer [PDF]

Revista da Associação Médica Brasileira, 2016
SUMMARY Introduction: Breast cancer is the second most common malignancy in the world and the one with highest incidence in the female population; it is also a major cause of death from cancer among women. Objective: To analyze the disease-free survival (DFS) at 5 years and prognostic factors in women with non-metastatic invasive breast cancer treated ...
Diniz, Roberta Wolp, Guerra, Maximiliano Ribeiro, Cintra, Jane Rocha Duarte, Fayer, Vívian Assis, Teixeira, Maria Teresa Bustamante   +4 more
openaire   +4 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A Systematic Review on Overall Survival and Disease-Free Survival Following Total Pelvic Exenteration

Asian Pacific Journal of Cancer Prevention, 2022
Total Pelvic Exenteration (TPE) is a radical operation for malignancies in which all of the organs inside the pelvic cavity, including the female reproductive organs, the lower urinary tract, and a part of the rectosigmoid are removed. In this study, we aimed to conduct a systematic review to assess the overall survival (OS) and disease-free survival ...
Miri, Seyed Rouhollah, Akhavan, Setareh, Mousavi, Azam Sadat, Hashemi, Seyedeh Razieh, Sheikhhasani, Shahrzad, Almasi-Hashiani, Amir, Fakhari, Mohammad Sadegh, Esmailzadeh, Arezoo   +7 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Prognostic significance of circulating tumor DNA detection and quantification in cervical cancer: a systematic review and meta-analysis

Frontiers in Oncology
BackgroundCirculating tumor DNA (ctDNA) is an emerging biomarker in cervical cancer, with elevated levels typically indicating a higher tumor burden. However, its prognostic value in cervical cancer patients remains debated.
Xiumin Zhao, Shufu Hou, Ruiqi Hao, Yelei Zang, Dandan Song   +4 more
doaj   +1 more source

The Emerging Roles and Mechanisms of PAQR3 in Human Cancer: Pathophysiology and Therapeutic Implications

International Journal of General Medicine, 2023
Qiang Guo,1,2,* Xiao-Li Liu,3,* Kui Zhai,4,* Cheng Chen,1 Xi-Xian Ke,1 Jun Zhang,2 Gang Xu1 1Department of Thoracic Surgery, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, People’s Republic of China; 2Department ...
Guo Q, Liu XL, Zhai K, Chen C, Ke XX, Zhang J, Xu G   +6 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Prognostic Nomogram for Disease-Free Survival in Patients with Renal Adenocarcinoma

Urologia Internationalis, 2012
<b><i>Objective:</i></b> The aim of this study was to develop a postoperative prognostic nomogram for disease-free survival in patients with renal adenocarcinoma. <b><i>Materials and Methods:</i></b> A total of 224 patients with organ-confined or locally advanced renal adenocarcinoma were treated with ...
Di Capua Sacoto, C., Budia, A., Garcia-Fadrique, G., Lujan, S., Ruiz-Cerda, J. L., Jimenez-Cruz, J. F.   +5 more
openaire   +3 more sources