Results 71 to 80 of about 1,961,991 (306)

Exploration of PET and MRI radiomic features for decoding breast cancer phenotypes and prognosis. [PDF]

, 2018
Radiomics is an emerging technology for imaging biomarker discovery and disease-specific personalized treatment management. This paper aims to determine the benefit of using multi-modality radiomics data from PET and MR images in the characterization ...
Arasu, Vignesh A, Behr, Spencer C, Copeland, Timothy P, Esserman, Laura, Franc, Benjamin L, Harnish, Roy J, Huang, Shih-Ying, Hylton, Nola M, Jones, Ella F, Kornak, John, Liu, Gengbo, Mitra, Debasis, Price, Elissa R, Seo, Youngho   +13 more
core  

Ras/Raf-1/MAPK pathway mediates response to tamoxifen but not chemotherapy in breast cancer patients [PDF]

, 2009
<b>Purpose</b>: The expression and activation of the Ras/Raf-1/mitogen-activated protein kinase (MAPK) pathway plays an important role in the development and progression of cancer, and may influence response to treatments such as tamoxifen ...
Bartlett, J.M.S., Cameron, D., Cooke, T.G., Edwards, J., Kirkegaard, T., McGlynn, L.M., Tovey, S., Twelves, C.   +7 more
core   +1 more source

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source

The Emerging Roles and Mechanisms of PAQR3 in Human Cancer: Pathophysiology and Therapeutic Implications

International Journal of General Medicine, 2023
Qiang Guo,1,2,* Xiao-Li Liu,3,* Kui Zhai,4,* Cheng Chen,1 Xi-Xian Ke,1 Jun Zhang,2 Gang Xu1 1Department of Thoracic Surgery, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, People’s Republic of China; 2Department ...
Guo Q, Liu XL, Zhai K, Chen C, Ke XX, Zhang J, Xu G   +6 more
doaj  

The Role of Complete Blood Count Parameters in Patients with Colorectal Cancer

Acta Clinica Croatica, 2018
Chronic inflammation has been linked with many cancers. It seems that easily available and usual blood inflammatory markers might serve as a prognostic factor for overall survival and disease-free survival in patients with various cancers.
Melih Solak Mekić, Ivo Pedišić, Hrvoje Šobat, Vanja Vučićević Boras, Iva Kirac, Ljilja Štefančić, Mario Šekerija, Borna Vrdoljak, Danko Velimir Vrdoljak   +8 more
doaj   +1 more source

Treatment of hepatic epithelioid hemangioendothelioma with liver transplantation [PDF]

, 1988
Ten patients received liver transplants for unresectable epithelioid hemangioendothelioma (EHE). At the time of transplantation, four patients had microscopic metastases to the hilar lymph nodes, and one of the four also had metastases to a rib.
Esquivel, CO, Iwatsuki, S, Kelleher, M, Klintmalm, G, Marino, IR, Starzl, TE, Todo, S, Tzakis, MG   +7 more
core   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

NRG Oncology/RTOG 0921: A phase 2 study of postoperative intensity-modulated radiotherapy with concurrent cisplatin and bevacizumab followed by carboplatin and paclitaxel for patients with endometrial cancer. [PDF]

, 2015
BACKGROUND: The current study was conducted to assess acute and late adverse events (AEs), overall survival (OS), pelvic failure, regional failure, distant failure, and disease-free survival in a prospective phase 2 clinical trial of bevacizumab and ...
Bosch, Walter R., Erickson, Beth A., Gaffney, David K., Horowitz, Neil S., Jhingran, Anuja, Mannel, Robert S S., Matulonis, Ursula A., Miller, Brigitte E., Moughan, Jennifer, Portelance, Lorraine, Small, William, Souhami, Luis, Viswanathan, Akila N., Winter, Kathryn A., Xiao, Ying   +14 more
core   +2 more sources

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment [PDF]

, 2000
BACKGROUND: The product of the Bcar1/p130Cas (breast cancer resistance/p130Crk-associated substrate) gene causes resistance to antiestrogen drugs in human breast cancer cells in vitro.
Brinkman, A. (Arend), Dorssers, L.C.J. (Lambert), Flier, S. (Silvia) van der, Foekens, J.A. (John), Klijn, J.G.M. (Jan), Kok, E.M. (Elisabeth), Look, M.P. (Maxime), Meijer van Gelder, M.E. (Marion)   +7 more
core   +1 more source