Results 71 to 80 of about 1,912,527 (212)

Erlotinib in patients with previously irradiated, recurrent brain metastases from non-small cell lung cancer: Two case reports [PDF]

, 2008
Background: With the current improvements in primary lung care, the long-term control of brain metastases becomes a clinical challenge. No established therapeutic approaches exist for cranial relapse after response to previous radiotherapy and systemic ...
Abrey LE, Barbara Poellinger, Ceresoli GR, Delattre Y, Horst Wagner, Hotta K, Joachim von Pawel, Khantia D, Lai CS, Namba Y, Regine WF, Rodrigus P, Thomas Duell, Zabel A   +13 more
core   +1 more source

Diabetes mellitus and poorer prognosis in hepatocellular carcinoma: a systematic review and meta-analysis.

PLoS ONE, 2014
BackgroundPrevious studies suggested that diabetes mellitus was associated with cancer risk and prognosis, but studies investigating the relationship between diabetes mellitus and survival in patients with hepatocellular carcinoma (HCC) reported ...
Yan-Gang Wang, Peng Wang, Bin Wang, Zheng-Ju Fu, Wen-Juan Zhao, Sheng-Li Yan   +5 more
doaj   +1 more source

Disease-free survival at 2 and 3 years is a significant early surrogate marker predicting the 5-year overall survival in patients treated with radical cystectomy for urothelial carcinoma of the bladder: external evaluation and validation in a cohort of Korean patients

Frontiers in Oncology, 2015
Purpose: We aimed to externally validate the association of 2- and 3-year disease-free survival with 5-year overall survival in patients treated with radical cystectomy for urothelial carcinoma of the bladder.
Hyung Suk eKim, Chang Wook eJeong, Cheol eKwak, Hyeon Hoe eKim, Ja Hyeon eKu   +4 more
doaj   +1 more source

Comparison of neoadjuvant cisplatin-based chemotherapy versus radiochemotherapy followed by resection for stage III (N2) NSCLC [PDF]

, 2017
Objective: Comparison of prospectively treated patients with neoadjuvant cisplatin-based chemotherapy vs radiochemotherapy followed by resection for mediastinoscopically proven stage III N2 non-small cell lung cancer with respect to postoperative ...
Guillou, Louis, Krueger, Thorsten, Pezzetta, Edgardo, Ris, Hans-Beat, Stupp, Roger, Taffé, Patrick, von Briel, Christian, Zouhair, Abderrahim   +7 more
core  

Interferon free antiviral treatment of chronic hepatitis C in patients affected by β-thalassemia major [PDF]

, 2017
Chronic hepatitis C (CHC) significantly affects the prognosis of liver disease [1] and health related quality of life (HRQOL) in patients with β-thalassemia major [2, 3].
Biliotti, Elisa, Esvan, Rozenn, Franchi, Cristiana, Palazzo, Donatella, Serani, Marco, Silvestri, Alessandro M., Sorrentino, Francesco, Spaziante, Martina, Taliani, Gloria, Volpicelli, Lorenzo   +9 more
core   +1 more source

Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy [PDF]

, 2013
Uracil in DNA is an important cause of mutagenesis. SMUG1 is a uracil DNA glycosylase that removes uracil through base excision repair. SMUG1 also processes radiation induced oxidative base damage as well as 5-fluorouracil incorporated into DNA during
Abdel-Fatah, TMA, Agarwal, D, Albarakati, N, Ball, G, Bowell, L, Chan, S, Ellis, IO, Hawkes, C, Madhusudan, S, Moseley, P   +9 more
core   +1 more source

Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women [PDF]

, 2017
To identify genetic variants associated with breast cancer prognosis we conduct a meta-analysis of overall survival (OS) and disease-free survival (DFS) in 6042 patients from four cohorts.
Blomqvist, Carl, Collins, Andrew, Couch, Fergus J., Durcan, Lorraine, Eccles, Diana, Fasching, Peter A., Gerty, Sue, Hopper, John L., Janni, Wolfgang, Kadalayil, Latha, Khan, Sofia, Liu, Jianjun, Maishman, Tom, Nevanlinna, Heli, Rack, Brigitte, Tapper, William   +15 more
core   +2 more sources

Methylation status of Wnt signaling pathway genes affects the clinical outcome of Philadelphia-positive acute lymphoblastic leukemia [PDF]

, 2008
The clinical significance of aberrant promoter methylation of the canonical Wnt pathway antagonist genes (sFRP1, sFRP2, sFRP4, sFRP5, Wif1, Dkk3, and Hdpr1) and also putative tumor-suppressor gene Wnt5a, belonging to the non-canonical Wnt signaling ...
Agirre-Ena, X. (Xabier), Castillejo, J.A. (J.A.), Cordeu, L. (Lucía), Garate, L. (Leire), Heiniger, A. (A.), Jimenez-Velasco, A. (A.), Martin, V. (Vanesa), Prosper, F. (Felipe), Roman-Gomez, J. (José), San-Jose, E. (Edurne), Torres, A. (Antonio), Vilas, A. (Amaia)   +11 more
core   +1 more source

Survival Outcome of Patients with Vaginal Malignancy: A 10-year Cohort Study from Tertiary Care Centre, Southern India

Journal of Clinical and Diagnostic Research
Introduction: Vaginal malignancy is a rare gynaecological malignancy, and authors know little about its survival and prognostic factors. The management of vaginal malignancies is largely determined by factors such as histological type, tumor size ...
Ramani Gangadharan Ashitha, Adarsh Dharmarajan, Geetha Muttath, PP Hiba   +3 more
doaj   +1 more source

Survival after initial lung metastasectomy for metastatic colorectal cancer in the modern chemotherapeutic era

BMC Surgery, 2017
Background A clear survival benefit has been reported for lung metastasectomy for colorectal cancer, and several clinicopathological prognostic factors have been proposed in the past.
Shintaro Yokoyama, Masahiro Mitsuoka, Tetsushi Kinugasa, Toshihiro Hashiguchi, Ryoichi Matsumoto, Daigo Murakami, Tatsuya Nishi, Koichi Yoshiyama, Masaki Kashihara, Shinzo Takamori, Yoshito Akagi   +10 more
doaj   +1 more source