Results 81 to 90 of about 27,151,543 (398)
HIF-1α is a Potential Molecular Target for Herbal Medicine to Treat Diseases
Drug Design, Development and Therapy, 2020 Ruo-Lan Li,1 Li-Ying He,1 Qing Zhang,1 Jia Liu,1 Feng Lu,1 Hu-Xin-Yue Duan,1 Lin-Hong Fan,1 Wei Peng,1 Yong-Liang Huang,2 Chun-Jie Wu1 1School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, People’s ...
Li RL +9 more
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Ecosphere, 2016 Global change drivers influence ecological processes at multiple scales and manifest across most of Earth as changes in biodiversity, biogeochemical cycles, infectious disease incidence, and ecohydrology.
Andrea S. Thorpe +9 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Acta Paediatrica, 1991 SummaryIn this review, I have outlined the clinical picture, epidemiology, pathology, etiology, and current treatment and management of Kawasaki disease. The disease in question has unique features which cannot be classified into any of the categories of conventional pediatric diseases, and thus the elucidation of the etiology and mode of onset may ...
openaire +7 more sources
Acta Veterinaria Scandinavica, 2001 The vertebral column of 124 randomly selected miniature dachshunds, representing 4.5% of the population registered by the Finnish Kennel Club during the years 1988 to 1996, were radiographed.
Snellman M +4 more
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Cholesterol Metabolism in T Cells
Frontiers in Immunology, 2017 Compartmentalization and spatial control of biochemical reactions is the foundation of cell-based life on earth. The lipid bilayer system employed by eukaryote cells not only keeps them separate from the environment but also provides a platform for key ...
Andreas Bietz +5 more
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Symbiosis and Dysbiosis of the Human Mycobiome
Frontiers in Microbiology, 2021 The influence of microbiological species has gained increased visibility and traction in the medical domain with major revelations about the role of bacteria on symbiosis and dysbiosis.
Kirtishri Mishra +6 more
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FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Phyllomedusa: Journal of Herpetology, 2019 Prevalence and pathology of Lernaea cyprinacea (Crustacea: Lernaeidae) parasitizing tadpoles of Pelophylax bedriagae (Anura: Ranidae) in Antalya, Turkey.
D. Innal, D. Sozbilen, O. Ozmen
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