Results 191 to 200 of about 5,753,304 (312)

PBMC transcriptomic signatures reflect immune dynamics and disease activity in psoriatic arthritis. [PDF]

Front Immunol
Hou R, Liu Y, Xue D, Wu R, Xu K, Zhang L.   +5 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Sjögren's disease metabolome reveals biomarker signatures to characterise patients and assess disease activity. [PDF]

RMD Open
Suffiotti M, Tanner L, Kozera L, Sebastian A, van Maurik A, Strasser D.   +5 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Inflammation response criteria for rheumatoid arthritis based on the two-component disease activity score. [PDF]

RMD Open
Stadler M, Rivellese F, Plant D, Nair N, Hyrich KL, Isaac J, Morgan A, Wilson AG, Verstappen SMM, Lewis MJ, Bowes J, Pitzalis C, Barton A.   +12 more
europepmc   +1 more source

Research Activities in Rheumatic Diseases [PDF]

Public Health Reports (1896-1970), 1954
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Utilization of aorta-specific fat attenuation index in evaluating disease activity and inflammation in Takayasu arteritis. [PDF]

Insights Imaging
Jian Z, Zhang H, Liu H, Sun J, Yang J, An Q, Luo J, Cheng L.   +7 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Novel Quantitative OCTA Biomarkers of Choroidal Neovascularization and Associations With Disease Activity and Etiology. [PDF]

Transl Vis Sci Technol
Gan Y, Pu J, Yang S, Chen X, Zhang X, Su Y, Li M, Wen F.   +7 more
europepmc   +1 more source