Results 151 to 160 of about 12,421,057 (398)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Estimating disease burden using Internet data [PDF]

open access: bronze, 2018
Riyi Qiu   +3 more
openalex   +1 more source

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019

open access: yesThe Lancet, 2021
Marissa B Parkes J Emad Cristiana Mohsen Amir Aidin E S De Reitsma Kendrick Ababneh Abbafati Abbasi-Kangevari   +485 more
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Is PEPFAR Funding for Key Populations Aligned with the Epidemiologic Burden? [PDF]

open access: yes, 2016
Key populations (KPs)—gay, bisexual, and other men who have sex with men (MSM); people who inject drugs (PWID), female sex workers (FSW); and transgender people (TG)—are at significantly higher risk for HIV, face a higher burden of disease, have less ...

core  

PM2.5-associated burden of disease and its cost in 429 Iranian counties from 2016 to 2018

open access: diamond, 2021
Sasan Faridi   +5 more
openalex   +1 more source

The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: a systematic review and meta-analysis [PDF]

open access: gold, 2023
Maureen Moyo-Chilufya   +5 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Are multiple coders needed for cause of death assignment: results from telephonic verbal autopsy interviews conducted in 2021 in South Africa

open access: yesDigital Health
Introduction Verbal autopsy (VA) methods have emerged to estimate causes of death in populations lacking robust civil registration and vital statistics (CRVS) systems.
Ian Neethling   +6 more
doaj   +1 more source

Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021

open access: yesThe Lancet Rheumatology, 2023
Jaimie D Steinmetz   +166 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy