Results 151 to 160 of about 1,359,990 (265)

Potential effect of real-world junk food and sugar-sweetened beverage taxes on population health, health system costs and greenhouse gas emissions in New Zealand: a modelling study

BMJ Nutrition, Prevention & Health
Tony Blakely, Anja Mizdrak, Cliona Ni Mhurchu, Amanda C Jones, Nhung Nghiem, Leah Grout, Christine Cleghorn   +6 more
doaj   +1 more source

Impact of Respiratory Viral Codetections on RSV Disease Burden in Young Children in Primary Care. [PDF]

Influenza Other Respir Viruses
Duijst L, Sankatsing V, Rizzo C, Baglivo F, Button E, Mariño MC, Sánchez MG, Hagemann C, de Lusignan S, Martyn O, Raes M, Van Brusselen D, Wildenbeest J, Hak S, Stelma F, van Summeren J, RSV ComNet network.   +16 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Urogenital congenital anomalies in children under 9 years: global disease burden analysis and projections, 1990-2021. [PDF]

J Pediatr (Rio J)
Gong S, Zhu J, Jiang G, Ruan W.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Ischemic heart disease burden and healthcare system readiness across sub-Saharan Africa. [PDF]

Nat Cardiovasc Res
Khurana MP, Bundgaard JS, Jeremiah K, Cichowitz C, Kisigo G, Ruselu G, Yan L, Kragh MV, Hasselbalch R, Ibáñez B, Praygod G, Faurholt-Jepsen D, Bundgaard H, Peck RN.   +13 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Disease burden of cervical cancer in China from 1990 to 2023 and prediction of future trends. [PDF]

Front Oncol
Yan T, Ma Q, Shi H, Qi D, Liu L.
europepmc   +1 more source

Prevention of HPV Disease Burden

Women's Health, 2014
Matti, Lehtinen, Pekka, Nieminen, Dan, Apter, Jorma, Paavonen   +3 more
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source