Results 181 to 190 of about 12,421,057 (398)
Global, regional, and national age-sex specific mortality for 264 causes of death, 1980–2016: a systematic analysis for the Global Burden of Disease Study 2016
The Lancet, 2017 Amanuel Alemu Cristiana Kaja M Foad Semaw Ferede Victor Ol Abajobir Abbafati Abbas Abd-Allah Abera Aboyans Ad, A. Abajobir, C. Abbafati, K. Abbas, F. Abd-Allah, S. Abera, V. Aboyans, O. Adetokunboh, A. Afshin, Anurag Agrawal, A. Ahmadi, M. Ahmed, Amani Nidhal Aichour, Miloud Taki Eddine Aichour, Ibtihel Aichour, Sneha Aiyar, Fares Alahdab, Z. Al-Aly, K. Alam, N. Alam, Tahiya Alam, K. Alene, A. Al-Eyadhy, Syed Danish Ali, Reza Alizadeh-Navaei, J. Alkaabi, A. Alkerwi, F. Alla, P. Allebeck, Christine Allen, R. Al-Raddadi, U. Alsharif, K. Altirkawi, N. Alvis-Guzmán, Azmeraw T. Amare, E. Amini, W. Ammar, Y. Amoako, N. Anber, H. Andersen, C. Andrei, S. Androudi, H. Ansari, C. Antonio, P. Anwari, J. Ärnlöv, Megha Arora, A. Artaman, K. Aryal, H. Asayesh, S. W. Asgedom, T. Atey, L. Ávila-Burgos, Euripide Avokpaho, A. Awasthi, T. Babalola, U. Bacha, K. Balakrishnan, A. Barać, M. Barboza, S. Barker-Collo, S. Barquera, L. Barregard, L. Barrero, B. Baune, Neeraj Bedi, E. Beghi, Y. Béjot, B. B. Bekele, M. Bell, James R. Bennett, I. Benseñor, A. Berhane, E. Bernabé, B. Betsu, M. Beuran, S. Bhatt, S. Biadgilign, Kelly Bienhoff, B. Bikbov, D. Bisanzio, R. Bourne, N. Breitborde, L. Bulto, Blair R Bumgarner, Z. Butt, Lucero Cahuana-Hurtado, E. Cameron, J. Campuzano, J. Car, Rosario Cárdenas, J. Carrero, A. Carter, Daniel C. Casey, C. Castañeda-Orjuela, F. Catalá-López, F. Charlson, C. Chibueze, Odgerel Chimed-Ochir, V. Chisumpa, Abdulaal Chitheer, D. Christopher, Liliana G. Ciobanu, M. Cirillo, A. Cohen, D. Colombara, C. Cooper, B. Cowie, M. Criqui, L. Dandona, R. Dandona, P. Dargan, J. D. das Neves, D. Davițoiu, K. Davletov, B. de Courten, B. K. Defo, L. Degenhardt, Selina Deiparine, Kebede Deribe, A. Deribew, Subhojit Dey, D. Dicker, E. Ding, S. Djalalinia, H. Do, D. Doku, Dirk Douwes-Schultz, T. Driscoll, M. Dubey, B. Duncan, M. Echko, Z. El-Khatib, C. Ellingsen, A. Enayati, H. Erskine, S. Eskandarieh, A. Esteghamati, Kara Estep, C. Farinha, Andre Faro, F. Farzadfar, V. Feigin, S. Fereshtehnejad, João Fernandes, A. Ferrari, T. R. Feyissa, I. Filip, Samuel Finegold, F. Fischer, C. Fitzmaurice, A. Flaxman, N. Foigt, Tahvi D Frank, Maya S. Fraser, N. Fullman, Thomas Fürst, J. Furtado, E. Gakidou, A. García-Basteiro, T. Gebre, G. Gebregergs, T. Gebrehiwot, Delelegn Yilma Gebremichael, J. Geleijnse, R. Gènova-Maleras, H. Gesesew, P. Gething, R. Gillum, M. Giroud, G. Giussani, W. Godwin, Audra L Gold, Ellen M. Goldberg, P. Gona, S. Gopalani, H. Gouda, A. Goulart, Max G Griswold, Rajeev Gupta, Tanush Gupta, Vipin Gupta, J. Haagsma, N. Hafezi-Nejad, A. Hailu, G. B. Hailu, R. Hamadeh, M. Hambisa, S. Hamidi, M. Hammami, Jamie Hancock, A. Handal, G. Hankey, Y. Hao, H. Harb, H. A. Hareri, Mohammad Sadegh Hassanvand, Rasmus J. Havmoeller, Simon Iain Hay, Fei He, M. Hedayati, N. Henry, I. Heredia-Pi, C. Herteliu, H. Hoek, M. Horino, N. Horita, H. Hosgood, S. Hostiuc, P. Hotez, D. Hoy, Chantal K Huynh, K. Iburg, C. Ikeda, B. Ileanu, Asnake Ararsa Irenso, C. Irvine, S. Islam, K. Jacobsen, N. Jahanmehr, M. Jakovljevic, Mehdi Javanbakht, S. Jayaraman, P. Jeemon, V. Jha, D. John, C. Johnson, Sarah C Johnson, J. Jonas, M. Jürisson, Z. Kabir, R. Kadel, Amaha Kahsay, R. Kamal, A. Karch, Seyed M. Karimi, Chante Karimkhani, A. Kasaeian, N. A. Kassaw, N. Kassebaum, S. Katikireddi, N. Kawakami, P. Keiyoro, L. Kemmer, C. Kesavachandran, Y. Khader, E. Khan, Y. Khang, A. Khoja, Mohammad Hossein Khosravi, A. Khosravi, J. Khubchandani, A. Kiadaliri, C. Kieling, Daniel R. Kievlan, Y. Kim, Daniel H. Kim, R. Kimokoti, Y. Kinfu, N. Kissoon, M. Kivimaki, A. Knudsen, J. Kopec, S. Kosen, P. Koul, A. Koyanagi, X. Kulikoff, G. Kumar, Pushpendra Kumar, Michael Kutz, H. Kyu, D. Lal, R. Lalloo, Tea Lallukka Nkurunziza Lambert, Q. Lan, V. Lansingh, A. Larsson, P. Lee, J. Leigh, J. Leung, M. Levi, Yongmei Li, Darya Li Kappe, Xiaofeng Liang, Misgan Legesse Liben, Stephen S. Lim, Patrick Y. Liu, Angela Liu, Yang Liu, R. Lodha, G. Logroscino, Alan D. Lopez, S. Lorkowski, P. Lotufo, R. Lozano, T. Lucas, Stefan Ma, Erlyn K Macarayan, Emilie Maddison, M. Magdy Abd El Razek, M. Majdan, R. Majdzadeh, A. Majeed, R. Malekzadeh, R. Malhotra, D. Malta, Helena Manguerra, Tsegahun Manyazewal, C. Mapoma, L. Marczak, D. Markos, J. Martínez-Raga, F. R. Martins-Melo, Ira Martopullo, C. McAlinden, Madeline McGaughey, J. Mcgrath, S. Mehata, T. Meier, K. G. Meles, P. Memiah, Z. Memish, M. M. Mengesha, D. T. Mengistu, Bereket Gebremichael Menota, G. Mensah, T. Meretoja, A. Meretoja, Anoushka I Millear, T. Miller, S. Minnig, M. Mirarefin, E. Mirrakhimov, A. Misganaw, S. Mishra, I. A. Mohamed, K. Mohammad, A. Mohammadi, S. Mohammed, A. Mokdad, G. Mola, Sarah K Mollenkopf, M. Molokhia, L. Monasta, J. Montañez, M. Montico, M. Mooney, M. Moradi-Lakeh, Paula Moraga, L. Morawska, C. Morozoff, S. Morrison, Cliff Mountjoy-Venning, K. Mruts, Kate Muller, C. Murray, G. Murthy, K. I. Musa, J. Nachega, M. Naghavi, A. Naheed, L. Naldi, V. Nangia, B. Nascimento, Jamal T Nasher, G. Natarajan, Ionut Negoi, J. Ngunjiri, C. Nguyen, Q. Nguyen, T. H. Nguyen, Grant Nguyen, Minh Nguyen, E. Nichols, D. N. A. Ningrum, V. M. Nong, J. Noubiap, F. Ogbo, I. Oh, Anselm Okoro, A. Olagunju, H. Olsen, B. Olusanya, J. Olusanya, K. Ong, John Nelson Opio, Eyal Oren, Alberto Ortiz, M. Osman, E. Ota, Mahesh Pa, R. Pacella, S. Pakhalé, A. Pana, B. Panda, S. Panda-Jonas, C. Papachristou, Eun‐Kee Park, S. Patten, G. Patton, Deepak Paudel, Katherine R Paulson, David M Pereira, F. Pérez-Ruiz, N. Perico, Aslam Pervaiz, M. Petzold, M. Phillips, D. Pigott, Christine Pinho, D. Plass, Martin A Pletcher, S. Polinder, M. Postma, F. Pourmalek, Caroline A. Purcell, M. Qorbani, B. Quintanilla, A. Radfar, V. Rahimi-Movaghar, Mohammad Hifz Ur Rahman, Mahfuzar Rahman, R. Rai, C. Ranabhat, Zane Rankin, P. Rao, G. Rath, S. Rawaf, S. E. Ray, J. Rehm, R. Reiner, M. Reitsma, G. Remuzzi, S. Rezaei, M. S. Rezai, M. Rokni, L. Ronfani, G. Roshandel, Gregory A. Roth, D. Rothenbacher, G. Ruhago, Rizwan Sa, S. Saadat, P. Sachdev, Nafis Sadat, M. Safdarian, S. Safi, S. Safiri, R. Sagar, R. Sahathevan, Joseph S. Salama, Payman Salamati, J. Salomon, A. Samy, J. Sanabria, M. Sánchez-Niño, D. Santomauro, I. Santos, M. Šantrić Milićević, B. Sartorius, Maheswar Satpathy, M. Schmidt, I. Schneider, Sam Schulhofer-Wohl, A. Schutte, D. Schwebel, F. Schwendicke, S. Sepanlou, E. Serván-Mori, K. Shackelford, S. Shahraz, M. Shaikh, M. Shamsipour, M. Shamsizadeh, Jayendra Sharma, Rajesh Sharma, Jun She, S. Sheikhbahaei, M. Shey, Chloe Shields, M. Shigematsu, R. Shiri, S. Shirude, I. Shiue, H. Shoman, M. Shrime, I. Sigfusdottir, Naris Silpakit, J. Silva, J. Singh, Abhishek Singh, Eirini Skiadaresi, Amber Sligar, David L. Smith, Alison Smith, Mari Smith, B. Sobaih, S. Soneji, Reed J. D. Sorensen, J. Soriano +499 moresemanticscholar +1 more sourceReduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh +8 morewiley +1 more sourceCytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock +10 morewiley +1 more sourceClass IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio +13 morewiley +1 more sourceIn vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow +10 morewiley +1 more sourceGlobal, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
The Lancet, 2016 Theo Christine Megha Ryan M Zulfiqar A Alexandria Austi Vos Allen Arora Barber Bhutta Brown Carter Casey C, T. Vos, Christine Allen, Megha Arora, Ryan Barber, Z. Bhutta, Alexandria Brown, A. Carter, Daniel C. Casey, F. Charlson, A. Z. Chen, M. Coggeshall, Leslie Cornaby, L. Dandona, D. Dicker, Tina Dilegge, H. Erskine, A. Ferrari, C. Fitzmaurice, T.D. Fleming, M. Forouzanfar, N. Fullman, P. Gething, Ellen M. Goldberg, Nicholas Graetz, J. Haagsma, C. Johnson, N. Kassebaum, Toana Kawashima, L. Kemmer, I. Khalil, Y. Kinfu, H. Kyu, Janni Leung, Xiaofeng Liang, Stephen S. Lim, A. D. Lopez, Rafael Lozano, L. Marczak, George A. Mensah, A. Mokdad, M. Naghavi, Grant Nguyen, E. Nsoesie, H. Olsen, D. Pigott, Christine Pinho, Zane Rankin, Nikolas Reinig, Joshua A. Salomon, Logan Sandar, Alison Smith, J. Stanaway, C. Steiner, Stephanie Teeple, Bernadette A. Thomas, C. Troeger, Joseph A Wagner, Haidong Wang, Valentine Wanga, H. Whiteford, Leo Zoeckler, A. Abajobir, K. H. Abate, C. Abbafati, K. Abbas, F. Abd-Allah, Biju Abraham, Ibrahim Abubakar, L. Abu-Raddad, Niveen M. E. Abu-Rmeileh, Ilana N. Ackerman, A. Adebiyi, Z. Ademi, A. K. Adou, K. Afanvi, E. Agardh, Arnav Agarwal, A. Kiadaliri, H. Ahmadieh, O. Ajala, R. Akinyemi, N. Akseer, Z. Al-Aly, K. Alam, N. Alam, S. Aldhahri, M. Alegretti, Z. A. Alemu, Lily T Alexander, Samia Alhabib, Raghib Ali, A. Alkerwi, François Alla, Peter Allebeck, R. Al-Raddadi, U. Alsharif, K. Altirkawi, N. Alvis-Guzmán, Azmeraw T. Amare, A. Amberbir, Heresh Amini, W. Ammar, Stephen M. Amrock, Hjalte H Andersen, G. M. Anderson, Benjamin O Anderson, C. Antonio, A. Aregay, Johan Ärnlöv, A. Artaman, H. Asayesh, Reza Assadi, S. Atique, Euripide Avokpaho, A. Awasthi, B. Quintanilla, P. Azzopardi, U. Bacha, A. Badawi, Kalpana Balakrishnan, Amitava Banerjee, A. Barać, S. Barker-Collo, T. Bärnighausen, L. Barregard, L. Barrero, Arindam Basu, S. Bazargan-Hejazi, B. Bell, Michelle L. Bell, Derrick A. Bennett, I. Benseñor, Habib Benzian, A. Berhane, Eduardo Bernabé, B. Betsu, A. Beyene, N. Bhala, Samir Bhatt, S. Biadgilign, Kelly Bienhoff, B. Bikbov, S. Biryukov, D. Bisanzio, Espen Bjertness, J. Blore, Rohan Borschmann, S. Boufous, Michael Brainin, A. Brazinova, N. Breitborde, Jonathan C. Brown, Rachelle Buchbinder, G. Buckle, Z. Butt, Bianca Calabria, Ismael Campos-Nonato, J. Campuzano, Hélène Carabin, Rosario Cárdenas, David O Carpenter, J. Carrero, C. Castañeda-Orjuela, Jacqueline Castillo Rivas, Ferrán Catalá-López, Jung-Chen Chang, P. Chiang, C. Chibueze, V. Chisumpa, J. Choi, Rajiv Chowdhury, H. Christensen, D. Christopher, Liliana G. Ciobanu, Massimo Cirillo, M. Coates, Samantha M. Colquhoun, Cyrus Cooper, Monica Cortinovis, J. Crump, S. Damtew, R. Dandona, Farah Daoud, P. Dargan, J. D. das Neves, Gail Davey, A. Davis, D. Leo, L. Degenhardt, L. Gobbo, R. Dellavalle, Kebede Deribe, A. Deribew, S. Derrett, D. Jarlais, S. Dharmaratne, Preeti Dhillon, C. Díaz-Torné, Eric L. Ding, T. Driscoll, Leilei Duan, M. Dubey, B. B. Duncan, H. Ebrahimi, R. Ellenbogen, Iqbal Elyazar, Matthias Endres, A. Endries, S. Ermakov, B. Eshrati, Kara Estep, Talha A Farid, C. Farinha, Andre Faro, M. Farvid, F. Farzadfar, Valery L. Feigin, David T. Felson, S. Fereshtehnejad, Jefferson G Fernandes, João C Fernandes, Florian Fischer, J. R. Fitchett, Kyle Foreman, F. G. R. Fowkes, Jordan Fox, R. C. Franklin, Joseph Friedman, Joseph Frostad, Thomas Fürst, Neal D Futran, B. Gabbe, Parthasarathi Ganguly, F. Gankpé, T. Gebre, T. Gebrehiwot, A. Gebremedhin, J. Geleijnse, Bradford D. Gessner, K. Gibney, I. Ginawi, A. Z. Giref, Maurice Giroud, Melkamu Dedefo Gishu, E. Glaser, W. Godwin, H. Gómez-Dantés, P. Gona, A. Goodridge, S. Gopalani, Carolyn C. Gotay, Atsushi Goto, H. Gouda, Rebecca Grainger, Felix Greaves, F. Guillemin, Yuming Guo, Rahul Gupta, Rajeev Gupta, Vipin Gupta, R. A. Gutiérrez, D. Haile, A. Hailu, G. B. Hailu, Y. Halasa, R. Hamadeh, S. Hamidi, M. Hammami, Jamie Hancock, A. Handal, Graeme J. Hankey, Yuantao Hao, H. Harb, S. Harikrishnan, J. Haro, Rasmus J. Havmoeller, Roderick J Hay, I. Heredia-Pi, P. Heydarpour, Hans W. Hoek, M. Horino, N. Horita, H. Hosgood, D. Hoy, A. Htet, Hsiang Huang, John J Emmanuel Huang, Chantal K Huynh, Marissa Iannarone, K. Iburg, K. Innos, M. Inoue, Veena J Iyer, K. Jacobsen, N. Jahanmehr, Mihajlo Jakovljevic, Mehdi Javanbakht, A. Jayatilleke, S. Jee, P. Jeemon, Paul N Jensen, Ying Jiang, T. Jibat, Aida Jimenez-Corona, Ye Jin, J. Jonas, Zubair Kabir, Y. Kalkonde, R. Kamal, Haidong Kan, André Karch, C. Karema, Chante Karimkhani, A. Kasaeian, Anil Kaul, Norito Kawakami, P. Keiyoro, A. H. Kemp, Andre Keren, C. Kesavachandran, Yousef S. Khader, Abdur Rahman Khan, E. Khan, Y. Khang, S. Khera, T. Khoja, J. Khubchandani, C. Kieling, Pauline Kim, Cho-il Kim, Daniel H. Kim, Y. Kim, N. Kissoon, Luke D. Knibbs, A. Knudsen, Y. Kokubo, D. Kolte, Jacek A. Kopec, S. Kosen, G. Kotsakis, P. Koul, Ai Koyanagi, M. Kravchenko, B. K. Defo, B. K. Bicer, A. Kudom, Ernst J Kuipers, G. Kumar, Michael Kutz, G. Kwan, Aparna Lal, R. Lalloo, T. Lallukka, H. Lam, Jennifer O Lam, S. Langan, Anders O. Larsson, P. Lavados, J. Leasher, J. Leigh, R. Leung, Miriam Levi, Yichong Li, Yongmei Li, Juan Liang, Shiwei Liu, Yang Liu, Belinda K Lloyd, Warren D. Lo, G. Logroscino, Katharine J Looker, P. Lotufo, R. Lunevicius, R. Lyons, M. Mackay, M. Magdy, A. Razek, M. Mahdavi, M. Majdan, Azeem Majeed, R. Malekzadeh, W. Marcenes, David J Margolis, J. Martínez-Raga, F. Masiye, J. Massano, S. Mcgarvey, John J McGrath, M. McKee, Brian J McMahon, P. Meaney, A. Mehari, Fabiola Mejía-Rodríguez, A. Mekonnen, Y. Melaku, P. Memiah, Ziad A. Memish, W. Mendoza, A. Meretoja, T. Meretoja, F. Mhimbira, Ted R. Miller, Edward J Mills, M. Mirarefin, Philip B Mitchell, Charles N Mock, Alireza Mohammadi, S. Mohammed, L. Monasta, J. M. Hernandez, M. Montico, M. Mooney, M. Moradi-Lakeh, L. Morawska, U. Mueller, Erin C. Mullany, J. Mumford, M. Murdoch, J. Nachega, Gabriele Nagel, A. Naheed, Luigi Naldi, V. Nangia, John N Newton, Marie Ng, F. Ngalesoni, Q. Nguyen, M. I. Nisar, P. M. N. Pete, J. M. Nolla, O. Norheim, Rosana E Norman, B. Norrving, B. P. Nunes, F. Ogbo, In-Hwan Oh, Takayoshi Ohkubo, Pedro R Olivares, B. Olusanya, J. Olusanya, Alberto Ortiz, M. Osman, E. Ota, Mahesh Pa, Eun-Kee Park, M. Parsaeian, Valéria Maria de Azeredo Passos, A. P. Caicedo, Scott B. Patten, George C. Patton, David M Pereira, Rogelio Pérez-Padilla, N. Perico, K. Pesudovs, M. Petzold, Michael Robert Phillips, F. Piel, J. Pillay, F. Pishgar, Dietrich Plass, J. Platts-Mills, S. Polinder, C. Pond, Svetlana Popova, Richie G. Poulton, F. Pourmalek, D. Prabhakaran, N. Prasad, Mostafa Qorbani, Rynaz Rabiee, A. Radfar, Anwar Rafay, Kazem Rahimi, V. Rahimi-Movaghar, Mahfuzar Rahman, Mohammad Hifz Ur Rahman, Sajjad Ur Rahman, R. Rai, Sasa Rajsic, U. Ram, P. Rao, A. Refaat, M. Reitsma, G. Remuzzi, S. Resnikoff, A.E. Reynolds, A. L. Ribeiro, M. Blancas, H. S. Roba, D. Rojas-Rueda, L. Ronfani, G. Roshandel, G. Roth, Dietrich Rothenbacher, Ambuj Roy, Rajesh Sagar, R. Sahathevan, Juan R Sanabria, Maria-Dolores Sanchez-Niño +499 moresemanticscholar +1 more sourceEffect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees +6 morewiley +1 more sourceMolecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed +12 morewiley +1 more source
