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The Lancet, 2012 Stephen S. Lim, T. Vos, A. Flaxman, G. Danaei, K. Shibuya, Heather Adair-Rohani, Mohammad A. Almazroa, M. Amann, H. R. Anderson, K. Andrews, M. Aryee, C. Atkinson, L. Bacchus, A. Bahalim, K. Balakrishnan, J. Balmes, S. Barker-Collo, A. Baxter, M. Bell, J. Blore, F. Blyth, C. Bonner, G. Borges, R. Bourne, M. Boussinesq, M. Brauer, P. Brooks, N. Bruce, B. Brunekreef, C. Bryan-Hancock, C. Bucello, R. Buchbinder, F. Bull, R. Burnett, T. Byers, Bianca Calabria, J. Carapetis, Emily Carnahan, Z. Chafe, F. Charlson, Honglei Chen, J. S. Chen, A. T. Cheng, J. C. Child, A. Cohen, K. Colson, B. Cowie, Sarah C. Darby, S. Darling, A. Davis, L. Degenhardt, F. Dentener, D. Jarlais, K. Devries, M. Dherani, E. Ding, E. Dorsey, T. Driscoll, K. Edmond, Suad Eltahir Ali, Rebecca E. Engell, P. Erwin, S. Fahimi, Gail Falder, F. Farzadfar, A. Ferrari, M. Finucane, S. Flaxman, F. Fowkes, Greg Freedman, Michael K. Freeman, E. Gakidou, Santu Ghosh, E. Giovannucci, G. Gmel, Kathryn Graham, R. Grainger, B. Grant, D. Gunnell, H. Gutierrez, Wayne Hall, H. Hoek, A. Hogan, H. Hosgood, D. Hoy, Howard Hu, B. Hubbell, S. Hutchings, Sydney E. Ibeanusi, G. Jacklyn, Rashmi Jasrasaria, J. Jonas, H. Kan, J. Kanis, N. Kassebaum, N. Kawakami, Y. Khang, S. Khatibzadeh, J. Khoo, Cindy Kok, F. Laden, R. Lalloo, Q. Lan, T. Lathlean, J. Leasher, J. Leigh, Yang Li, J. Lin, S. Lipshultz, S. London, R. Lozano, Yuan Lu, J. Mak, R. Malekzadeh, Leslie Mallinger, W. Marcenes, L. March, Robert G. Marks, R. Martin, P. McGale, J. Mcgrath, S. Mehta, Z. Memish, G. Mensah, T. Merriman, R. Micha, C. Michaud, V. Mishra, Khayriyyah Mohd Hanafiah, A. Mokdad, L. Morawska, D. Mozaffarian, Tasha B. Murphy, M. Naghavi, B. Neal, P. Nelson, J. Nolla, Rosana E Norman, Casey Olives, S. Omer, J. Orchard, R. Osborne, B. Ostro, A. Page, K. Pandey, C. Parry, E. Passmore, Jayadeep Patra, N. Pearce, P. Pelizzari, M. Petzold, M. Phillips, D. Pope, C. Pope, J. Powles, M. Rao, H. Razavi, E. Rehfuess, J. Rehm, B. Ritz, F. Rivara, Thomas J Roberts, Carolyn Robinson, J. A. Rodriguez-Portales, I. Romieu, R. Room, Lisa C Rosenfeld, Ananya Roy, L. Rushton, J. Salomon, Uchechukwu Sampson, L. Sànchez-Riera, Ella Sanman, A. Sapkota, S. Seedat, P. Shi, K. Shield, R. Shivakoti, Gitanjali M Singh, D. Sleet, Emma Smith, Kirk R. Smith, Nicolas J. C. Stapelberg, K. Steenland, H. Stöckl, L. Stovner, K. Straif, L. Straney, G. Thurston, Jimmy H. Tran, R. Dingenen, A. Donkelaar, J. Veerman, L. Vijayakumar, Robert Weintraub, M. Weissman, Richard A. White, H. Whiteford, S. Wiersma, J. Wilkinson, H. Williams, Warwick Williams, N. Wilson, A. Woolf, P. Yip, J. Zielinski, Alan D. Lopez, C. Murray, M. Ezzati +208 moresemanticscholar +1 more sourceGlobal burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019
EClinicalMedicine, 2023 S. Momtazmanesh, S. Moghaddam, S. Ghamari, E. M. Rad, N. Rezaei, Parnian Shobeiri, Amirali Aali, M. Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Michael Abdelmasseh, M. Abdoun, Deldar Morad Abdulah, Abu Yousuf Md Abdullah, Aidin Abedi, Hassan Abolhassani, Zahra Abrehdari-Tafreshi, B. Achappa, Denberu Eshetie Adane Adane, T. D. Adane, Isaac Yeboah Addo, Mohammad Adnan, Qorinah Estiningtyas Sakilah Adnani, Sajjad Ahmad, A. Ahmadi, K. Ahmadi, A. Ahmed, Ayman Ahmed, Rebwar Khalid Hamad, Hanadi Al Hamad, F. Alahdab, Astawus Alemayehu, S. M. Alif, S. Aljunid, Sami A. Almustanyir, K. Altirkawi, N. Alvis-Guzmán, J. A. Dehkordi, M. Amir-Behghadami, R. Ancuceanu, C. Andrei, Tudorel Andrei, Catherine M. Antony, A. Anyasodor, J. Arabloo, Judie Arulappan, Tahira Ashraf, S. Athari, E. Attia, Meshesha Tsegazeab Ayele, S. Azadnajafabad, A. Babu, S. Bagherieh, Ovidiu Constantin Baltatu, Maciej Banach, Mainak Bardhan, Francesco Barone-Adesi, Amadou Barrow, S. Basu, N. Bayileyegn, I. Benseñor, Nikha Bhardwaj, Pankaj Bhardwaj, A. N. Bhat, Krittika Bhattacharyya, S. Bouaoud, D. Braithwaite, Michael Brauer, M. H. Butt, Z. Butt, D. Calina, L. Cámera, Gashaw Sisay Chanie, P. Charalampous, Vijay Kumar Chattu, Odgerel Chimed-Ochir, D. Chu, Aaron J. Cohen, N. Cruz-Martins, O. Dadras, A. Darwesh, Saswati Das, Sisay Abebe Debela, Laura Delgado-Ortiz, Diriba Dereje, M. Dianatinasab, Nancy Diao, Daniel Diaz, Lankamo Ena Digesa, Gebisa Dirirsa, Paul Narh Doku, Deepa Dongarwar, A. Douiri, Haneil Larson Dsouza, E. Eini, Michael Ekholuenetale, T. Ekundayo, Ahmed Elabbas Mustafa Elagali, Muhammed Elhadi, Daniel Berhanie Enyew, Ryenchindorj Erkhembayar, Farshid Etaee, A. Fagbamigbe, Andre Faro, A. Fatehizadeh, Ginenus Fekadu, I. Filip, F. Fischer, M. Foroutan, R. C. Franklin, Péter Gaál, Santosh Gaihre, A. Gaipov, Mesfin Gebrehiwot, Urge Gerema, M. Getachew, Tamiru Getachew, Mansour Ghafourifard, R. Ghanbari, A. Ghashghaee, A. 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Rodrigues, Jefferson Antonio Buendia Rodriguez, L. Roever, D. Rojas-Rueda, K. Rudd, Al Saad, S. Sabour, B. Saddik, E. Sadeghi, M. Sadeghi, U. Saeed, Maryam Sahebazzamani, A. Sahebkar, H. Sahoo, M. Sajid, S. Sakhamuri, Salehi, A. Samy, Milena M. Santric-Milicevic, Bruno Piassi Sao Jose, B. Sathian, Maheswar Satpathy, G. Saya, S. Senthilkumaran, Allen Seylani, S. Shahabi, M. Shaikh, Mohd Shanawaz, Mohammed Shannawaz, R. Sheikhi, Shashank Shekhar, M. Sibhat, Colin Simpson, Jasvinder A. Singh, Paramdeep Singh, Surjit Singh, V. Skryabin, A. Skryabina, M. Soltani‐Zangbar, Suhang Song, Ireneous N. Soyiri, P. Steiropoulos, Leo Stockfelt, Jing Sun, Ken Takahashi, I. Talaat, Ker-Kan Tan, Nathan Y. Tat, Vivian Y. Tat, Birhan Tsegaw Taye, P. Thangaraju, Rekha Thapar, F. Thienemann, A. Tiyuri, Mai Thi Ngoc Tran, J. Tripathy, L. T. Car, B. S. Tusa, I. Ullah, Sana Ullah, M. Vacante, Pascual Valdez, R. Valizadeh, Job F. M. van Boven, T. Vasankari, Siavash Vaziri, F. Violante, Bay Vo, Ning Wang, M. Wei, R. Westerman, N. Wickramasinghe, Suowen Xu, Xiaoyue Xu, Lalit Yadav, Y. Yismaw, D. Yon, N. Yonemoto, Chuanhua Yu, Yong Yu, Ismaeel Yunusa, M. Zahir, M. Zangiabadian, Z. Zareshahrabadi, Armin Zarrintan, M. Zastrozhin, Z. Zegeye, Yunquan Zhang, M. Naghavi, B. Larijani, F. Farzadfar +413 moresemanticscholar +1 more sourceTranscriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal +16 morewiley +1 more sourceEffective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet +17 morewiley +1 more sourceMonitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien +35 morewiley +1 more source
