Results 241 to 250 of about 12,421,057 (398)

Potential effect of real-world junk food and sugar-sweetened beverage taxes on population health, health system costs and greenhouse gas emissions in New Zealand: a modelling study

BMJ Nutrition, Prevention & Health
Tony Blakely, Anja Mizdrak, Cliona Ni Mhurchu, Amanda C Jones, Nhung Nghiem, Leah Grout, Christine Cleghorn   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Pericardial segmentation: a proposed model to quantify disease burden. [PDF]

Open Heart
Giliomee LJ, Verster J, Maposa I, Doubell A, Robbertse PS, Herbst P.   +5 more
europepmc   +1 more source

Estimating the burden of disease from water, sanitation, and hygiene at a global level. [PDF]

, 2002
Annette Prüss, David Kay, Lorna Fewtrell, Jamie Bartram   +3 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Association of Obesity Severity With Cardiometabolic and Renal Disease Burden in the United States. [PDF]

Obesity (Silver Spring)
Corpodean F, Kachmar M, Yang S, Heymsfield SB, Katzmarzyk PT, Schauer PR, Cook MW, Albaugh VL.   +7 more
europepmc   +1 more source

The burdens of digestive diseases [PDF]

Nature Reviews Gastroenterology & Hepatology, 2009
openaire   +2 more sources

Global, regional and national burden of tracheal, bronchus, and lung cancer attributable to ambient particulate matter pollution from 1990 to 2021: an analysis of the global burden of disease study [PDF]

Jianguo Lü, Xiangmei Zhao, Shu Gan
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Systematic Literature Reviews on the Disease Burden of Pediatric Psoriasis. [PDF]

Dermatol Ther (Heidelb)
Sanchez SZ, Tran T, Garcia A, Telukuntla V, Pillai S, Horgan J, Deignan C.   +6 more
europepmc   +1 more source