Results 141 to 150 of about 9,539,267 (257)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Adenovirus Nanoparticles Displaying RBD Induce a Protective Immune Response Against BA.5 in Mice

International Journal of Nanomedicine
Chuncong Mo,1,2,* Zhongfang Wang,1,2,* Donglan Liu,2,* Xiaoyun Yang,2,* Qiong Zhang,2 Lihua Ye,1 Shuai Yuan,3 ShiDong Deng,1 Zhulan Lai,2 Deyi Huang,1 Yujie Yang,1,2 Duo Xu,2 Jinwei Yuan,2 Yuhui Zhu,1 Haoyi Liu,1 Chengxing
Mo C, Wang Z, Liu D, Yang X, Zhang Q, Ye L, Yuan S, Deng S, Lai Z, Huang D, Yang Y, Xu D, Yuan J, Zhu Y, Liu H, Zhou C, Liao X, Li X, Liu W, Zhou R, Tian X   +20 more
doaj  

Alzheimer's Disease Detection Using Combined EEG Source Connectivity and Microstate Features. [PDF]

Brain Sci
Huang L, Hu Z, Zhang Z, Gao Y.
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Preventing Chronic Disease (PCD) [PDF]

This collection of articles in Preventing Chronic Disease (PCD) brings together scientists and practitioners from the breadth of public health and the social sciences to demonstrate how geospatial perspectives can contribute to understanding and ...

core  

AgroPatch AutoStrike for adversarial patch attacks on plant disease detection models. [PDF]

iScience
Wu Y, Wang M, Jin X, Dai Y, Liu L, Yuan W, Ye Y, Zhu Z, Gu L, Zhang Y.   +9 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Query-based multimodal interaction and adaptive gated fusion for Alzheimer's disease detection. [PDF]

Front Aging Neurosci
Shao Y, Tan C, Huo H, Fang T.
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Advanced molecular detection and response to infectious disease outbreaks [PDF]

Advanced molecular detection and response to infectious disease outbreaks : in 2014, CDC focused AMD efforts on transforming the response to infectious disease outbreaks by makingsignificant leaps in genomic sequencing and bioinformatics capabilities ...

core