Results 151 to 160 of about 9,539,267 (257)

Multiparametric MRI for Early Chronic Kidney Disease Detection: Insights Into Renal Microcirculation. [PDF]

NMR Biomed
Zha T, Pan L, Yang Y, Du Y, Chen Y, Wen Q, Chen J, Jiang Z, Xing W.   +8 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Antibiotics confound breath-based respiratory disease detection in calves. [PDF]

PLoS One
Langford B, Brans J, Broadbent C, Gibson T, Hanlon M, Haskell M, Nicoll L, Mullinger NJ, Duthie CA.   +8 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Spotted fever group, typhus group rickettsioses and sennetsu neorickettsiosis in rural Thailand

International Journal of Infectious Diseases, 2014
S. Bhengsri, H.C. Baggett, S. Edouard, S.F. Dowell, G. Watt, D. Raoult, P. Parola   +6 more
doaj   +1 more source

Multimodal Deep Learning Approaches for Lung Disease Detection: A Review. [PDF]

Medicina (Kaunas)
Estay Zamorano B, Dehghan Firoozabadi A, Adasme P, Montiel Piña W, Muñoz MC, Zabala-Blanco D, Palacios Játiva P, Azurdia-Meza CA.   +7 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

YOLOv11-MPD: A Multi-Part Maize Disease Detection Algorithm for Complex Field Environments. [PDF]

Sensors (Basel)
Dong R, Jin L, Cai Z.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

The Association of FIT-Based Colorectal Cancer Screening with Earlier Disease Detection: The Romanian Experience. [PDF]

Cancers (Basel)
Dutei CA, Richiteanu G, Grama FA, Becheanu G, Cotruta B, Manuc TE, Chifulescu AE, Manuc M.   +7 more
europepmc   +1 more source