Results 51 to 60 of about 9,539,267 (257)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Determination of 8 polycyclic aromatic hydrocarbons in fried oil for churros using GC-MS

open access: yesZhongguo shipin weisheng zazhi
ObjectiveA method for the determination of PAH8 in fried oil for churros was developed by modified SPE-GC/MS.MethodsThe target analytes in samples were saponified by KOH/Ethanol, extracted with n-hexane and cleaned-up by solid phase extraction column ...
DONG Xinfeng   +4 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Beyond iodine nutrition: socioeconomic patterns independently drive thyroid disease risk in pregnant women in Xinjiang

open access: yesFrontiers in Nutrition
ObjectiveTo investigate the impact of distinct socioeconomic status (SES) patterns on the risk of thyroid diseases in pregnant women against the background of adequate iodine nutrition.MethodsA cross-sectional study was conducted in Xinjiang from 2021 to
Jing Zhou   +7 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Preclinical detection of infectivity and disease-specific PrP in blood throughout the incubation period of prion disease [PDF]

open access: yes, 2015
Variant Creutzfeldt-Jakob disease (vCJD) is a fatal neurodegenerative disorder characterised by accumulation of pathological isoforms of the prion protein, PrP. Although cases of clinical vCJD are rare, there is evidence there may be tens of thousands of
Jackson, G.S.   +4 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

RANK-BASED TEMPO-SPATIAL CLUSTERING: A FRAMEWORK FOR RAPID OUTBREAK DETECTION USING SINGLE OR MULTIPLE DATA STREAMS [PDF]

open access: yes, 2012
In the recent decades, algorithms for disease outbreak detection have become one of the main interests of public health practitioners to identify and localize an outbreak as early as possible in order to warrant further public health response before a ...
Que, Jialan
core  

Evolutionary and genotypic analyses of goose astrovirus

open access: yesPoultry Science
Based on 183 complete genome sequences of Goose Astrovirus (GAstV), this study systematically elucidated the molecular epidemiological characteristics and evolutionary patterns of the virus.
Mingxiang Li   +6 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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