Results 61 to 70 of about 9,539,267 (257)
Global Disease Detection : detecting and containing health threats [PDF]
GDD operates as CDC\u2019s platform for developing and strengthening global capacity to rapidly detect, accurately identify, and promptly contain emerging infectious disease and bioterrorist threats that occur internationally.Enhancing global health ...
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Pathogenic characteristics of Vibrio parahaemolyticus O10:K4 in Guangdong Province from 2020 to 2022
Zhongguo shipin weisheng zazhiObjectiveTo investigate the drug resistance， molecular characteristics and prevalence of Vibrio parahaemolyticus O10：K4 in Guangdong Province from 2020 to 2022， and to provide evidence for the prevention and control of Vibrio parahaemolyticus infection ...
ZOU Min +8 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Global disease detection : advancing the science of global public health [PDF]
Did You Know\ue2\u20ac\ua2 Three of the top 10 causes of death globally are from infectious diseases?\ue2\u20ac\ua2 Most of these deaths are occurring in low- and middle-income countries?\ue2\u20ac\ua2 About 2/3 of the world\ue2\u20ac\u2122s countries ...
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Frontiers in ImmunologyIntroductionSARS-CoV-2 undergoes persistent genomic evolution, yet prevalent circulating variants tend to evolve toward reduced pathogenicity. However, direct comparative pathogenesis data involving contemporary, immune-evasive strains—such as the ...
Xiaofang Peng +16 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Global Disease Detection Operations Center : tracking global outbreaks [PDF]
The Global Disease Detection Operations Center monitors outbreaks across the globe and assesses their potential risk to the global community.The Operations Center was established in 2007 to address weaknesses or gaps in global public health surveillance ...
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source