Results 91 to 100 of about 20,357,001 (365)

Comparison of Frequentist and Bayesian Meta-Analysis Models for Assessing the Efficacy of Decision Support Systems in Reducing Fungal Disease Incidence

Agronomy, 2020
Diseases of fruit and foliage caused by fungi and oomycetes are generally controlled by the application of fungicides. The use of decision support systems (DSSs) may assist to optimize fungicide programs to enhance application on the basis of risk ...
Elena Lázaro, David Makowski, Joaquín Martínez-Minaya, Antonio Vicent   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Annual and Post-Exacerbation Follow-Up of Asthma Patients in Clinical Practice – A Large Population-Based Study in Sweden

Journal of Asthma and Allergy, 2022
Hanna Sandelowsky,1– 3 Björn Ställberg,4 Fredrik Wiklund,5 Gunilla Telg,6 Sofie de Fine Licht,6 Christer Janson7 1Karolinska Institutet, Department of Medicine, Division of Clinical Epidemiology, Solna, Sweden; 2Karolinska Institutet, Department of ...
Sandelowsky H, Ställberg B, Wiklund F, Telg G, de Fine Licht S, Janson C   +5 more
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Repeat-induced point mutations driving Parastagonospora nodorum genomic diversity are balanced by selection against non-synonymous mutations

Communications Biology
Parastagonospora nodorum is necrotrophic fungal pathogen of wheat with significant genomic resources. Population-level pangenome data for 173 isolates, of which 156 were from Western Australia (WA) and 17 were international, were examined for overall ...
Darcy A. B. Jones, Kasia Rybak, Mohitul Hossain, Stefania Bertazzoni, Angela Williams, Kar-Chun Tan, Huyen T. T. Phan, James K. Hane   +7 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

EffectorFisher: association of disease phenotype with pangenomic protein-isoform profiles for improved prediction of fungal pathogenicity effectors

Scientific Reports
Plant-pathogenic fungi cause crop disease via a range of secreted effector proteins that interact with specific receptors of host plant cells. Effector identification can enable the diagnosis of disease outcomes and enable selection or breeding of ...
Mohitul Hossain, Naomi Gray, Pavel Misiun, Kristina Gagalova, Eiko Furuki, Kasia Clarke, Leon Lenzo, Hossein Golzar, Manisha Shankar, Huyen Phan, James Hane   +10 more
doaj   +1 more source

AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease

Hepatology, 2023
M. Rinella, B. Neuschwander‐Tetri, M. Siddiqui, M. Abdelmalek, S. Caldwell, D. Barb, D. Kleiner, R. Loomba   +7 more
semanticscholar   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

An Architecture Model for Multiple Disease Management Information Systems

, 2014
Disease management is a program which attempts to overcome the fragmentation of healthcare system and improve the quality of care. Many studies have proven the effectiveness of disease management.
游惠珠 ;莊立民 ;彭惠鈺, Chen, Lichin;Yu, Hui-Chu;Li, Hao-Chun;Wang, Yi-Van;Chen, Huang-Jen;Wang, I-Ching;Wang, Chiou-Shiang;Peng, Hui-Yu;Hsu, Yu-Ling;Chen, Chi-Huang;Chuang, Lee-Ming;Lee, Hung-Chang;Chung, Yufang;Lai, Feipei   +1 more
core   +1 more source