Results 231 to 240 of about 565,742 (268)
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Trends in Molecular Medicine, 2001
Mutations in the APC gene are responsible for familial adenomatous polyposis (FAP) and for the majority of sporadic colorectal cancers. The establishment of genotype-phenotype correlations in FAP is often complicated by the great clinical variability observed among carriers of the same APC mutation even within the same kindred.
Fodde, Riccardo, Smits, Ron
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Mutations in the APC gene are responsible for familial adenomatous polyposis (FAP) and for the majority of sporadic colorectal cancers. The establishment of genotype-phenotype correlations in FAP is often complicated by the great clinical variability observed among carriers of the same APC mutation even within the same kindred.
Fodde, Riccardo, Smits, Ron
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iPSC-based disease modeling and drug discovery in cardinal neurodegenerative disorders
Cell Stem Cell, 2022Hideyuki Okano, Satoru Morimoto
exaly
Abstract Animal disease models provide valuable pre-clinical information to support progression of agents into human clinical studies. Examples of disease models by indication illustrate the diversity of the field.
Phil Ambery +2 more
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Phil Ambery +2 more
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Real-Time Infectious Disease Modeling to Inform Emergency Public Health Decision Making
Annual Review of Public Health, 2022Anna Bershteyn +2 more
exaly
2002
AbstractThis chapter discusses the concept of a model for the disease process, emphasizing simple and very general models that can be used to study a variety of diseases. Quantities that are used to describe this fundamental model are the hazard function, the survival function, and the failure time density function.
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AbstractThis chapter discusses the concept of a model for the disease process, emphasizing simple and very general models that can be used to study a variety of diseases. Quantities that are used to describe this fundamental model are the hazard function, the survival function, and the failure time density function.
openaire +1 more source
A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling
Cell, 2019Yimu Zhao +2 more
exaly