Results 231 to 240 of about 1,245,538 (288)
Engineering Three-Dimensional Cellular Organization by Regulating Bound Water-Mediated Cell-Substrate Interactions for Disease Modeling. [PDF]
Kawahara M +4 more
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Assessing Public Health Capacity for Infectious Disease Modeling: A Qualitative Study of State and Local Agencies. [PDF]
Crouch SJ +6 more
europepmc +1 more source
Engineering biomimetic tissue barrier models on chips: From design and fabrication to applications in disease modeling and drug screening. [PDF]
Nasiri R +21 more
europepmc +1 more source
Base editors in zebrafish: a new era for functional genomics and disease modeling. [PDF]
Liu Y +10 more
europepmc +1 more source
Cardiac organoids: a new tool for disease modeling and drug screening applications. [PDF]
Yaqinuddin A +15 more
europepmc +1 more source
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Disease model: Parkinson's disease
Trends in Molecular Medicine, 2003Parkinson's disease (PD) is a progressive neurodegenerative disorder that is primarily characterized by the degeneration of dopaminergic neurons in the nigrostriatal pathway. The pathology of PD is typified by the presence of cytoplasmic inclusions (Lewy bodies) containing alpha-synuclein and ubiquitin.
Shun, Shimohama +3 more
openaire +2 more sources
2022
Mathematical models are essential components of the toolbox of any disease ecologist. They should be used as an integral part of any investigation into the impact and management of infectious disease in wildlife populations. Simple models are important to conceptualize the processes occurring during host–pathogen interactions and to identify key ...
Johannes Foufopoulos +2 more
openaire +1 more source
Mathematical models are essential components of the toolbox of any disease ecologist. They should be used as an integral part of any investigation into the impact and management of infectious disease in wildlife populations. Simple models are important to conceptualize the processes occurring during host–pathogen interactions and to identify key ...
Johannes Foufopoulos +2 more
openaire +1 more source
2018
Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. It is known that there are many factors, either genetic or environmental factors, involved in PD, but the mechanism of PD is still not fully understood. Several animal models have been established to study the mechanisms of PD.
Vuu My, Dung, Dang Thi Phuong, Thao
openaire +2 more sources
Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. It is known that there are many factors, either genetic or environmental factors, involved in PD, but the mechanism of PD is still not fully understood. Several animal models have been established to study the mechanisms of PD.
Vuu My, Dung, Dang Thi Phuong, Thao
openaire +2 more sources
2018
Osteochondral (OC) lesions are a major cause of chronic musculoskeletal pain and functional disability, which reduces the quality of life of the patients and entails high costs to the society. Currently, there are no effective treatments, so in vitro and in vivo disease models are critically important to obtain knowledge about the causes and to develop
Gema, Jiménez +4 more
openaire +2 more sources
Osteochondral (OC) lesions are a major cause of chronic musculoskeletal pain and functional disability, which reduces the quality of life of the patients and entails high costs to the society. Currently, there are no effective treatments, so in vitro and in vivo disease models are critically important to obtain knowledge about the causes and to develop
Gema, Jiménez +4 more
openaire +2 more sources
Modeling gastrointestinal anthrax disease
Research in Microbiology, 2023Bacillus anthracis is a spore-forming microbe that persists in soil and causes anthrax disease. The most natural route of infection is ingestion by grazing animals. Gastrointestinal (GI) anthrax also occurs in their monogastric predators, including humans.
Oh, So Young +6 more
openaire +4 more sources

