Results 261 to 270 of about 666,620 (307)
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2018
Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. It is known that there are many factors, either genetic or environmental factors, involved in PD, but the mechanism of PD is still not fully understood. Several animal models have been established to study the mechanisms of PD.
Vuu My, Dung, Dang Thi Phuong, Thao
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Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. It is known that there are many factors, either genetic or environmental factors, involved in PD, but the mechanism of PD is still not fully understood. Several animal models have been established to study the mechanisms of PD.
Vuu My, Dung, Dang Thi Phuong, Thao
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2022
Mathematical models are essential components of the toolbox of any disease ecologist. They should be used as an integral part of any investigation into the impact and management of infectious disease in wildlife populations. Simple models are important to conceptualize the processes occurring during host–pathogen interactions and to identify key ...
Johannes Foufopoulos +2 more
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Mathematical models are essential components of the toolbox of any disease ecologist. They should be used as an integral part of any investigation into the impact and management of infectious disease in wildlife populations. Simple models are important to conceptualize the processes occurring during host–pathogen interactions and to identify key ...
Johannes Foufopoulos +2 more
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British Journal of Medical Psychology, 1993
This paper describes and analyses six models of health and disease. These are: religious, biomedical, psychosomatic, humanistic, existential and transpersonal. Of these six models, only one was unequivocally reductionist: the biomedical. The others were all holistic.
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This paper describes and analyses six models of health and disease. These are: religious, biomedical, psychosomatic, humanistic, existential and transpersonal. Of these six models, only one was unequivocally reductionist: the biomedical. The others were all holistic.
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Disease models of autoimmunity
Trends in Immunology, 2005The dream of producing medically relevant scientific observations, which are then translated successfully into therapeutic modalities, is the driving force behind much laboratory research. Such noble aspirations have, however, been soured by an underlying stand-off between basic researchers and clinicians.
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Modeling of Parkinson's Disease in Different Models
CNS & Neurological Disorders - Drug TargetsParkinson's Disease (PD) is a progressive disorder worldwide and its etiology remains unidentified. Over the last few decades, animal models of PD have been extensively utilized to explore the development and mechanisms of this neurodegenerative condition.
Iqra, Subhan, Yasir Hasan, Siddique
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Neuromuscular Disease Models and Analysis
2009Neuromuscular diseases can affect the survival of peripheral neurons, their axons extending to peripheral targets, their synaptic connections onto those targets, or the targets themselves. Examples include motor neuron diseases such as amyotrophic lateral sclerosis, peripheral neuropathies, such as Charcot-Marie-Tooth diseases, myasthenias, and ...
Burgess, Robert W +2 more
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Zebrafish as a Model of Cardiac Disease
2014The zebrafish has been rapidly adopted as a model for cardiac development and disease. The transparency of the embryo, its limited requirement for active oxygen delivery, and ease of use in genetic manipulations and chemical exposure have made it a powerful alternative to rodents.
Wilkinson, R. N. +2 more
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Modeling Tick-Borne Disease: A Metapopulation Model
Bulletin of Mathematical Biology, 2006Recent increases in reported outbreaks of tick-borne diseases have led to increased interest in understanding and controlling epidemics involving these transmission vectors. Mathematical disease models typically assume constant population size and spatial homogeneity. For tick-borne diseases, these assumptions are not always valid.
Gaff, Holly D., Gross, Louis J.
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Drosophila Models of Parkinson's Disease☆
2011Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder principally affecting the dopaminergic neurons of the substantia nigra. The pathogenic mechanisms are unknown and there are currently no cure or disease-modifying therapies.
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Trends in Molecular Medicine, 2001
Mutations in the APC gene are responsible for familial adenomatous polyposis (FAP) and for the majority of sporadic colorectal cancers. The establishment of genotype-phenotype correlations in FAP is often complicated by the great clinical variability observed among carriers of the same APC mutation even within the same kindred.
Fodde, Riccardo, Smits, Ron
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Mutations in the APC gene are responsible for familial adenomatous polyposis (FAP) and for the majority of sporadic colorectal cancers. The establishment of genotype-phenotype correlations in FAP is often complicated by the great clinical variability observed among carriers of the same APC mutation even within the same kindred.
Fodde, Riccardo, Smits, Ron
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