Results 261 to 270 of about 16,121,002 (311)

Animal models of Cushing's disease

Trends in Endocrinology & Metabolism, 1994
Cushing's disease, defined as hyperadrenocorticism resulting from excessive secretion of pituitary ACTH, occurs spontaneously and quite commonly in dogs and horses. In dogs, as in humans, the disease is usually associated with a small tumor of the pituitary pars distalis.
R J, Kemppainen, M, E Peterson
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Animal models of Parkinson's disease

BioEssays, 2002
AbstractAnimal models are important tools in experimental medical science to better understand pathogenesis of human diseases. Once developed, these models can be exploited to test therapeutic approaches for treating functional disturbances observed in the disease of interest. On the basis of experimental and clinical findings, Parkinson's disease (PD)
Ranjita, Betarbet, Todd B, Sherer, J Timothy, Greenamyre   +2 more
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Animal Models of Nonthyroidal Disease*

Endocrine Reviews, 1985
Rats bearing transplantable Walker 256 carcinoma provide an opportunity to assess thyroid function and activity during an interval of time when the tumor has not affected growth rate. Rats with tumor have decreased serum T4 and T3 concentration and decreased serum FT4 and FT3 as well.
J M, Tibaldi, M I, Surks
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Parkinson's disease: animal models

2007
Publisher Summary Animal models are an essential tool to study human diseases, not only to enable a thorough investigation into the mechanisms involved in the pathogenesis of a disease but also to help in the development of therapeutic strategies. This chapter describes genetic as well as pharmacological manipulations used to develop animal models ...
Ranjita, Betarbet, J Timothy, Greenamyre
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