Neurovascular-metabolic dysregulation, metabolic connectomics, and metabolic functional changes in Alzheimer's disease: A preclinical and clinical comparison. [PDF]
Chong Chie JAK +6 more
europepmc +1 more source
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source
Human-animal contact and zoonotic exposure from wild and domestic animals: A cross-sectional study in wildlife-rich areas of Bolivia, Chile, and Guatemala. [PDF]
Kuhn C +9 more
europepmc +1 more source
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
Susceptibility and transcriptional characteristics of inbred C57BL/6J and outbred ICR mice in CDAHFD-induced MASH models. [PDF]
Zhou J +9 more
europepmc +1 more source
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu +14 more
wiley +1 more source
Diet, Metabolism and Synaptic Function: Integrating Evidence Across Models in Neurodegeneration Research. [PDF]
Targett IL, Hancock JT, Craig TJ.
europepmc +1 more source
Animal organoids as transformative platforms for viral infections and zoonotic cross-species viral research. [PDF]
García-Rodríguez I +3 more
europepmc +1 more source
Bioengineering Applications of Chinese Herbal Medicine-Derived Exosomes in Cardiovascular Diseases: Mechanisms and Translational Prospects. [PDF]
Liu Y, Wang Y, Fang M.
europepmc +1 more source

