Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Completion of early response actions accounted for most elapsed time across the 7-1-7 pathway in Sierra Leone, 2023-2025. [PDF]
Ikoona EN +4 more
europepmc +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
MMWR. Morbidity and Mortality Weekly Report, Vol. 70, No. 46, November 19, 2021
Prevalence and Characteristics of Subjective Cognitive Decline Among Unpaid Caregivers Aged 6545 Years \u2014 22 States, 2015\u20132019 / Eva M. Jeffers; Erin D. Bouldin; Lisa C. McGuire; Kenneth A.
core
Este estudo analisou a confiabilidade do diagnóstico final das 155.242 notificações de dengue da epidemia 2001-2002 no Município do Rio de Janeiro, fornecidas pela Secretaria Municipal de Saúde do Rio de Janeiro, por meio do Sistema de Informação de ...
Ana Lucia Araujo de Toledo +3 more
doaj
Pre-screening village tuberculosis notification rates and the yield of interferon-gamma release assay testing in a rural health-examination campaign in Xinjiang, China. [PDF]
He W +6 more
europepmc +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Digitalization of the Mandatory Notifications System for Infectious Diseases in Germany: Implementation of DEMIS (the German Electronic Reporting and Information System). [PDF]
Suwono B +7 more
europepmc +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Transforming a Pandemic Tool Into a Public Health Asset: Modified Delphi Study. [PDF]
Malekinejad M +5 more
europepmc +1 more source

