Results 181 to 190 of about 10,577,757 (334)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Estimating the velocity and direction of African Swine Fever spread in wild boar populations in South Korea using Trend-Surface Analysis. [PDF]

PLoS One
Aguilar-Vega C, Bosch J, Ito S, Ivorra B, Jeong H, Sánchez-Vizcaíno JM.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Epidemiological and digital syndromic surveillance data on dengue, chikungunya, and SARI in Brazil. [PDF]

Sci Data
Borges ME, Codeço CT, Machado D, Almeida A.   +3 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Potential impact and acceptability of Internet partner notification for men who have sex with men and transgender women recently diagnosed as having sexually transmitted disease in Lima, Peru.

Sexually Transmitted Diseases, 2014
J. Clark, Eddy R. Segura, Amaya G. Perez-Brumer, S. Reisner, J. Peinado, H. Salvatierra, Jorge Sanchez, J. Lama   +7 more
semanticscholar   +1 more source

Elevated Pertussis Reporting in Response to 2011–2012 Outbreak, New York City, New York, USA

Emerging Infectious Diseases, 2016
Robert J. Arciuolo, Jennifer B. Rosen, Jane R. Zucker   +2 more
doaj   +1 more source

Epidemiological and spatial-temporal clustering characteristics of pertussis in Southwest China, 2013-2024. [PDF]

Front Public Health
Wang J, Xu J, Xiao D, Li B, Xiong Y, Yang J, Wei W, Chen L, Wang Q, Qin Y, Liu Y, Zhao H, Long J, Qi L.   +13 more
europepmc   +1 more source

Consent and Confidentiality in Adolescent Health Care by Pediatricians: A Private Practice Viewpoint [PDF]

, 1983
Bell, Reed
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source