Results 191 to 200 of about 10,577,757 (334)

Armed conflict intensity and inequalities in tuberculosis outcomes in Colombia municipalities, 2008-2019. [PDF]

BMJ Glob Health
Valencia-Aguirre S, Castañeda-Orjuela CA, Gutiérrez-Clavijo JC, Cotes-Cantillo K, Garcia-Basteiro AL.   +4 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Adapting Back-calculation Methods to Estimate the Incidence of Tuberculosis. [PDF]

Epidemiology
Shapiro AN, Mohammed S, Horsburgh CR, Jenkins HE, White LF.   +4 more
europepmc   +1 more source

Hypothesis: Cryptosporidium genetic diversity mirrors national disease notification rate. [PDF]

Parasit Vectors, 2015
Takumi K, Cacciò SM, van der Giessen J, Xiao L, Sprong H.   +4 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Diagnostic shifts in extrapulmonary tuberculosis during COVID-19: evidence of vulnerability among migrants in a border province. [PDF]

BMC Infect Dis
Çil B, Bodur MS, Kabak M.
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Legionnaires' disease in France: sensitivity of the mandatory notification has improved over the last decade

Epidemiology and Infection, 2013
C. Campèse, S. Jarraud, C. Sommen, C. Maine, D. Che   +4 more
semanticscholar   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Can a TB outbreak be detected by reviewing the surveillance data? [PDF]

Public Health Action
Yamaguchi R, Umezawa T, Date N, Furusawa W, Maeki T, Uchimura K, Hirao S, Ota M.   +7 more
europepmc   +1 more source