Results 91 to 100 of about 70,504 (293)
Identification of cis-regulatory modules in mouse embryonic limb buds and heart using endogenous epitope-tagged transcription factors [PDF]
, 2014 The genes that control mouse embryonic development are tightly regulated spatially and temporally by the integration of various signaling pathways. The interaction of downstream transcription factors with cis-regulatory modules located in the genomic ...
Laurent, Frédéric
core +1 more source
Advanced Functional Materials, EarlyView.A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang +9 more
wiley +1 more source
Restoring heart function and electrical integrity: closing the circuit
npj Regenerative Medicine, 2017 Cardiovascular diseases are the main cause of death in the world and are often associated with the occurrence of arrhythmias due to disruption of myocardial electrical integrity.
Luís Miguel Monteiro +4 more
doaj +1 more source
Noninvasive cardiac assessment in children of women with systemic lupus erythematosus
Arquivos Brasileiros de Cardiologia, 2003 OBJECTIVE: Noninvasive cardiac assessment of newborns and infants of women with systemic lupus erythematosus. The children had no congenital total atrioventricular block and were compared with the children of healthy women.
Maria de Fátima Monteitro Pereira Leite +8 more
doaj +1 more source
Specification of the cardiac conduction system by transcription factors
, 2009 Diseases of the cardiovascular system that cause sudden cardiac deaths are often caused by lethal arrhythmias that originate from defects in the cardiac conduction system.
Basson, Craig T., Hatcher, Cathy J.
core
The Roles of Neuregulin-1 in Cardiac Development, Homeostasis, and Disease
, 2015 Neuregulin-1 (NRG-1) and its signaling receptors, erythroblastic leukemia viral oncogene homologs (ErbB) 2, 3, and 4, have been implicated in both cardiomyocyte development and disease, as well as in homeostatic cardiac function.
Kareen L.K. Coulombe, Cassady E. Rupert
core +1 more source
Advanced Healthcare Materials, EarlyView.We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
wiley +1 more source
Cardiac conduction arteries in infants: Early atherosclerotic lesions of fibromuscular hyperplasia/dysplasia? [PDF]
, 2005 Aims Aim of the present study is to examine in 70 infants dying suddenly the morphologic structure of the cardiac conduction system arteries.Background Although early atherosclerotic lesions of the coronary arteries detectable in infants and even in ...
L. Matturri, G. Ottaviani, AM. Lavezzi
core
Gene regulatory elements of the cardiac conduction system
, 2014 The coordinated contraction of the heart relies on the generation and conduction of the electrical impulse. Aberrations of the function of the cardiac conduction system have been associated with various arrhythmogenic disorders and increased risk of ...
Christoffels, Vincent M. +2 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang +7 more
wiley +1 more source