Results 241 to 250 of about 12,599,414 (356)
Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease
Nature Network Boston, 2019 O. Preische, Stephanie A. Schultz, Anja Apel, J. Kuhle, S. Kaeser, Christian Barro, S. Gräber, Elke Kuder-Buletta, C. Lafougère, C. Laske, J. Vöglein, J. Levin, C. Masters, R. Martins, P. Schofield, M. Rossor, N. Graff-Radford, S. Salloway, B. Ghetti, J. Ringman, James M. Noble, J. Chhatwal, A. Goate, T. Benzinger, J. Morris, R. Bateman, Guoqiao Wang, A. Fagan, E. McDade, B. Gordon, M. Jucker, Ricardo Fatima Randall Tammie Sarah Courtney Susan William Allegri Amtashar Bateman Benzinger Berman Bodge Br, R. Allegri, Fatima S. Amtashar, R. Bateman, T. Benzinger, S. Berman, Courtney A. Bodge, S. Brandon, W. Brooks, Jill Buck, V. Buckles, Sochenda Chea, J. Chhatwal, Patricio Chrem, H. Chui, J. Cinco, J. Clifford, Carlos Cruchaga, Mirelle D’Mello, Tamara Donahue, J. Douglas, Noelia Edigo, Nilufer Erekin-Taner, A. Fagan, M. Farlow, Angela M. Farrar, H. Feldman, Gigi Flynn, Nick C Fox, E. Franklin, H. Fujii, Cortaiga Gant, S. Gardener, B. Ghetti, A. Goate, J. Goldman, B. Gordon, N. Graff-Radford, Julia D. Gray, J. Gurney, Jason Hassenstab, Mie Hirohara, D. Holtzman, R. Hornbeck, Siri Houeland DiBari, T. Ikeuchi, Snezana Ikonomovic, Gina Jerome, M. Jucker, C. Karch, K. Kasuga, T. Kawarabayashi, W. Klunk, R. Koeppe, Elke Kuder-Buletta, C. Laske, Jae-Hong Lee, D. Marcus, R. Martins, N. Mason, C. Masters, Denise Maue-Dreyfus, E. McDade, Lucy Montoya, H. Mori, J. Morris, Akem Nagamatsu, Katie Neimeyer, James M. Noble, J. Norton, R. Perrin, M. Raichle, J. Ringman, J. Roh, S. Salloway, P. Schofield, H. Shimada, Tomoyo Shiroto, M. Shoji, Wendy C. Sigurdson, H. Sohrabi, Paige Sparks, Kazushi Suzuki, Laura M Swisher, K. Taddei, Jen C. Wang, Peter Wang, M. Weiner, Mary A. Wolfsberger, C. Xiong, Xiong Xu +121 moresemanticscholar +1 more sourceA DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée +11 morewiley +1 more sourceDapagliflozin, in addition to ramipril, ameliorates kidney disease progression in mice with Alport syndrome. [PDF]
Am J Physiol Renal PhysiolMiyata KN, Smith DM, Yamashita M, Kim S, Yeargin FA, Beganovic M, Zhang SL, Chan JSD, Miner JH, Leal DN, Li JP, Bruno J. +11 moreeuropepmc +1 more sourceEvaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing
Molecular Oncology, EarlyView.Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled +10 morewiley +1 more sourceMulti-scale machine learning model predicts muscle and functional disease progression. [PDF]
Sci RepBlemker SS, Riem L, DuCharme O, Pinette M, Costanzo KE, Weatherley E, Statland J, Tapscott SJ, Wang LH, Shaw DWW, Song X, Leung D, Friedman SD. +12 moreeuropepmc +1 more sourceCytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén +13 morewiley +1 more sourceLevodopa treatment: impacts and mechanisms throughout Parkinson's disease progression. [PDF]
J Neural Transm (Vienna)Riederer P, Strobel S, Nagatsu T, Watanabe H, Chen X, Löschmann PA, Sian-Hulsmann J, Jost WH, Müller T, Dijkstra JM, Monoranu CM. +10 moreeuropepmc +1 more source