Results 291 to 300 of about 12,789,497 (387)

Understanding the nature of renal disease progression

, 1997
Giuseppe Remuzzi, Piero Ruggenenti, Ariela Benigni   +2 more
openalex   +1 more source

Imperial strategy of cancer cells through mitochondrial transfer

Molecular Oncology, EarlyView.
Cangkrama et al. demonstrated that cancer cells donate their mitochondria to fibroblasts through mitochondrial transfer, reprogramming them into ‘MitoCAF’. Likewise, our group has identified mitochondrial transfer from cancer cells to tumor infiltrating lymphocytes, resulting in mitochondrial ‘hijack’ and impaired antitumor immunity.
Takamasa Ishino, Yosuke Togashi
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Anti-Osteoporosis Treatment Alleviates Osteoarthritis Symptoms and Partially Reverses Disease Progression. [PDF]

Orthop Surg
Feng Z, Yin H, Ding Y, Sun X, Zhang T, Guo A.   +5 more
europepmc   +1 more source

Prevention of disease progression, left ventricular hypertrophy and congestive heart failure in hypertension treatment trials

, 1996
Marvin Moser, Patricia R. Hebert
openalex   +1 more source

Natural history of periodontitis: Disease progression and tooth loss over 40 years

Journal of Clinical Periodontology, 2017
C. Ramseier, Å. Ånerud, M. Dulac, Martina Lulić, M. Cullinan, G. Seymour, M. Faddy, W. Bürgin, M. Schätzle, N. Lang   +9 more
semanticscholar   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Statin effect on arrhythmogenic cardiomyopathy disease progression (SEARCH): Randomized clinical study protocol. [PDF]

PLoS One
Sommariva E, Lippi M, Bruttini F, Cannata F, Baggiano A, Schiavone M, Salina G, Sabatino M, Vettor G, Sicuso R, Pizzamiglio F, Ribatti V, Maragna R, Carbucicchio C, DeLuca F, Catto V, Iezzi A, Salè EO, Valeri Y, Barbarossa A, Caiazza M, Monda E, Frisso G, Borrelli F, Gasperetti A, Turco A, De Luca L, Corino VDA, Galotta A, Bonomi A, Pompilio G, Pontone G, Muratori M, Limongelli G, Lombardi R, Casella M, Tondo C.   +36 more
europepmc   +1 more source

3D Printing of Tissue Engineered Constructs for In Vitro Modeling of Disease Progression and Drug Screening

Annals of Biomedical Engineering, 2016
Joseph P. Vanderburgh, J. Sterling, S. Guelcher   +2 more
semanticscholar   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source