Results 121 to 130 of about 8,964,528 (267)
Advancing Agricultural Resilience: Omics Strategies Unveiling Molecular Mechanisms for Disease Resistance In Vegetables [PDF]
In modern agriculture, the cultivation of vegetables faces significant challenges due to the relentless onslaught of various diseases that can lead to substantial crop losses.
Ali Hassan Khan +1 more
core +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
, 2016 Key findings »» Ancient barley germplasm from Ethiopia harbours resistance to scald and other diseases. »» Twenty-eight out of 355 Ethiopian lines were moderately resistant to scald. »» Careful selection for disease-resistant lines is important to retain
Adorada, Dante, Milgate, Andrew
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Improving the diversity of resistance mechanisms available in wheat to combat Fusarium Ear Blight disease [PDF]
, 2009 Fusarium ear blight (FEB) is a disease of wheat and small grain cereals, caused by the fungi Fusarium culmorum and Fusarium graminearum. The disease causes premature bleaching of spikelets and shrivelling of the grain can result in a direct yield loss.
Holdgate, Sarah, Holdgate, S.
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
AMD and response to infectious disease outbreaks [PDF]
A total of $40 million requested in Budget Authority for Advanced Molecular Detection and Response to Infectious Disease Outbreaks. CDC currently lacks the molecular sequencing tools and bioinformatics capacity to meet the demands of today's rapidly ...
Centers for Disease Control and Prevention (U.S.)
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
This program reviews with the aid of drawings the nurse's role in the prevention of disease. Emphasis is placed on factors which influence the transmission of disease.
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