Results 171 to 180 of about 1,587,717 (295)

Disease Resistance In Cabbage [PDF]

open access: yesProceedings of the National Academy of Sciences, 1918
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

A Transmembrane Protein WAI-B2 Confers Multiple Disease Resistance in Wheat by Activating Autoimmunity. [PDF]

open access: yesAdv Sci (Weinh)
Li W   +32 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Targeting effector proteins of plant pathogens as a strategy for durable plant disease resistance. [PDF]

open access: yesFront Microbiol
Senthilraja G   +5 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Harnessing primary, secondary and tertiary genepools for durable wheat disease resistance. [PDF]

open access: yesTheor Appl Genet
Blower A   +5 more
europepmc   +1 more source

Leveraging Wild Tomato Relatives for Durable Disease Resistance: Advances, Challenges, and Genomic Prospects

open access: green
Ampah-Korsah Jessica   +7 more
openalex   +1 more source

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